ID   A0A3B4B1T3_9GOBI        Unreviewed;       447 AA.
AC   A0A3B4B1T3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=GDNF family receptor alpha {ECO:0000256|PIRNR:PIRNR038071};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000022536.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000022536.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004609};
CC       Lipid-anchor, GPI-anchor {ECO:0000256|ARBA:ARBA00004609}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004589}; Lipid-anchor, GPI-anchor
CC       {ECO:0000256|ARBA:ARBA00004589}.
CC   -!- SIMILARITY: Belongs to the GDNFR family.
CC       {ECO:0000256|ARBA:ARBA00005961, ECO:0000256|PIRNR:PIRNR038071}.
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DR   AlphaFoldDB; A0A3B4B1T3; -.
DR   Ensembl; ENSPMGT00000024004.1; ENSPMGP00000022536.1; ENSPMGG00000018154.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0098552; C:side of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.220.110; GDNF binding domain; 1.
DR   InterPro; IPR016017; GDNF/GAS1.
DR   InterPro; IPR037193; GDNF_alpha.
DR   InterPro; IPR003438; GDNF_rcpt.
DR   InterPro; IPR017372; Glial_neurotroph_fac_rcpt_a1/2.
DR   PANTHER; PTHR10269:SF3; GDNF FAMILY RECEPTOR ALPHA-1; 1.
DR   PANTHER; PTHR10269; GDNF RECEPTOR ALPHA; 1.
DR   Pfam; PF02351; GDNF; 3.
DR   PIRSF; PIRSF038071; GDNF_family_receptor_alpha; 1.
DR   PRINTS; PR01316; GDNFRECEPTOR.
DR   SMART; SM00907; GDNF; 3.
DR   SUPFAM; SSF110035; GDNF receptor-like; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR038071};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   GPI-anchor {ECO:0000256|ARBA:ARBA00022622};
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR038071};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR038071};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          24..106
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
FT   DOMAIN          145..228
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
FT   DOMAIN          238..332
FT                   /note="GDNF/GAS1"
FT                   /evidence="ECO:0000259|SMART:SM00907"
FT   REGION          356..376
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   447 AA;  49994 MW;  E06A0CEE57A958C2 CRC64;
     YFINLIYIAL LKGDGASRSV PMDCVKASEQ CLREYSCSTK YRTMRQCVAG RESNFSAVTG
     PEAQGECRSA IEAMKQSPLY RCRCRRGMKK EKNCLRIFWS IFQSLQGNDL LEYSPYEPVN
     SRLSDIFRLA PIIAGKPPST KENNCLSAAK ACNLNDTCKK YRSAYINPCT SRVSASEVCN
     KRKCHKALRH FFDKVPTKYS YGMLFCSCPA GDQTACAERR RQTIVPVCSY EDKDKPNCLS
     LQNTCKANYI CRSRLADFLS NCQPEPRSIS GCLRENYADC LLSYSGLIGT VMTPNYVRSQ
     GISLSPWCDC SSSGNNKPDC DRFNQFFSDN RCLRNAIQAF GNGTDVGVWQ PQPPIEPTEP
     GLTRTRTRDQ NSNSLDTLTD MSRLDLNSDS AFNTCGMQNH PLDESSSNAI ARSGSHGPLS
     SHPLTLLLAI LFSLPSSVKF YEGFRLW
//