ID A0A3B4BAK2_9GOBI Unreviewed; 532 AA.
AC A0A3B4BAK2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Transcription factor E2F7 {ECO:0000256|ARBA:ARBA00039675};
OS Periophthalmus magnuspinnatus.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000026548.1, ECO:0000313|Proteomes:UP000261520};
RN [1] {ECO:0000313|Ensembl:ENSPMGP00000026548.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU003796}.
CC -!- SIMILARITY: Belongs to the E2F/DP family.
CC {ECO:0000256|ARBA:ARBA00010940, ECO:0000256|RuleBase:RU003796}.
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DR AlphaFoldDB; A0A3B4BAK2; -.
DR STRING; 409849.ENSPMGP00000026548; -.
DR Ensembl; ENSPMGT00000028271.1; ENSPMGP00000026548.1; ENSPMGG00000021412.1.
DR Proteomes; UP000261520; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR015633; E2F.
DR InterPro; IPR003316; E2F_WHTH_DNA-bd_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12081; TRANSCRIPTION FACTOR E2F; 1.
DR PANTHER; PTHR12081:SF25; TRANSCRIPTION FACTOR E2F7; 1.
DR Pfam; PF02319; E2F_TDP; 2.
DR SMART; SM01372; E2F_TDP; 2.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU003796};
KW Nucleus {ECO:0000256|RuleBase:RU003796};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU003796};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU003796}.
FT DOMAIN 138..207
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT DOMAIN 255..339
FT /note="E2F/DP family winged-helix DNA-binding"
FT /evidence="ECO:0000259|SMART:SM01372"
FT REGION 48..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..253
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 532 AA; 60022 MW; 7DFD1D188443F29F CRC64;
KMEVDCLALK DLTSPRKSYA TKENLFLERR STPLKSTDAA LALLLNRKGS SPDPAHMTPI
KHSSSAEPWT PTANLKMLIS AASPDIRDRE MKKVLFRPIE NETELPKSPE LIIEEDADVD
DSQFEALEED ETEKKPSRKQ KSLGLLCQKF LALYPDDPPP NSPIWISLDK VANSLGVERR
RIYDIVNVLE SLMIVGRMAK NSYSWYGRRR LESKLMELQR RGREQGYHLQ MEPGEGNGES
NPQPGSNPLL KPTSDKDKSL RIMSQKFVML FLVSKTQTVT LDAAAKILIE DSQDSSHSKY
KTKVRRLYDI ANVLTSLGLI KKVHVREERG RKPAFKWRGP TEFNSTGPLP PTGLEASQRI
TQQDLTRLKM SRHSSFNITP TSVTVQRQAN SAPNSPRREH TGTVIDFATF VHCTFFFIRA
VVSCPQHILL MQSLSGQMLT SSPPPPPSSS HSHCLTYLPS LSQPSVVMLY RAAEGHRSPG
MEGEEMRKRK REGEEMSMAK KGVNGLKKSD EVKMCNYLIM LLKEHYVTFL AC
//
