ID   A0A3B4BHI8_9GOBI        Unreviewed;       720 AA.
AC   A0A3B4BHI8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D {ECO:0008006|Google:ProtNLM};
OS   Periophthalmus magnuspinnatus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Oxudercinae; Periophthalmus.
OX   NCBI_TaxID=409849 {ECO:0000313|Ensembl:ENSPMGP00000029054.1, ECO:0000313|Proteomes:UP000261520};
RN   [1] {ECO:0000313|Ensembl:ENSPMGP00000029054.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the semaphorin family.
CC       {ECO:0000256|ARBA:ARBA00009492}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B4BHI8; -.
DR   STRING; 409849.ENSPMGP00000029054; -.
DR   Ensembl; ENSPMGT00000030927.1; ENSPMGP00000029054.1; ENSPMGG00000023379.1.
DR   Proteomes; UP000261520; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR   GO; GO:0007411; P:axon guidance; IEA:UniProt.
DR   CDD; cd05871; Ig_Sema3; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013151; Immunoglobulin.
DR   InterPro; IPR016201; PSI.
DR   InterPro; IPR001627; Semap_dom.
DR   InterPro; IPR036352; Semap_dom_sf.
DR   InterPro; IPR027231; Semaphorin.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR11036; SEMAPHORIN; 1.
DR   PANTHER; PTHR11036:SF36; SEMAPHORIN-3D; 1.
DR   Pfam; PF00047; ig; 1.
DR   Pfam; PF01403; Sema; 1.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00423; PSI; 1.
DR   SMART; SM00630; Sema; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF101912; Sema domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS51004; SEMA; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           16..720
FT                   /note="Sema domain, immunoglobulin domain (Ig), short basic
FT                   domain, secreted, (semaphorin) 3D"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017337720"
FT   DOMAIN          1..483
FT                   /note="Sema"
FT                   /evidence="ECO:0000259|PROSITE:PS51004"
FT   DOMAIN          516..630
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   REGION          686..720
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   720 AA;  81765 MW;  BAAFA1FA4FC94B8F CRC64;
     MLICFLVFVA DLVQAGSVSV LLGPSDGLHS HTLLLDEERG RLLLGARDHI YLLDPDNPDK
     TPRKIHWPAS RERVDMCRQA GKNPTLECAN FVRVLHNYNH THLYACGTGA FHPICAYLRI
     TGNTEVRIIK ESGRLKCPFD PAQPFTSVLT DQFLYSGTSS DFLGKDASFT RSLGPTPDQH
     YIRTEISQDY WINEAKFISA HSISDTYNPD DDKIYFFFRE ASREGSDKSI VSRVARVCKN
     DMGGLRSLTH KWTTFLKARL VCSVPGEDGV DTHFDQLQDI FMLPSRDEKN TKVYAVFTTS
     SSLFPGSAVC VYNMADIRAV FNGPYAHKES PDHKWVEYDG RIPYPRPGTC PSKTYDPRIK
     STKDFPDEVV SFMRMHPLMQ RSVSPVGGRP VFTRLRADYT LTHIRVDRVM AEDGHYEVMF
     LGTDIGSVLK VVSISQENWA TEEVILEELQ VFQTPSPILS MEISSKQQVL LVGSALGLSR
     VSLSRCPVYG QACAECCLAR DPYCAWDGHS CARYIPAAKR RARRQDIKNG DPATQCWDTE
     DRKGVEEKLI FGIEKNSTFL ECVAKSQQAQ ILWTFQRAGS ERREEIKADD RMLYTTRGLL
     IRSVRPSDAG SYTCLAQEHS HFTHTLLKIK LQLVTHVQLA SKPGEETHLK AESKQHYKDY
     LRVMSAPYGS LEEYCDSLWL EKRPSRAKGK GLGSSKWKHM QEMKKNRNRR HHVKAEEVQR
//