ID A0A3B4BPX8_PYGNA Unreviewed; 354 AA.
AC A0A3B4BPX8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Guanine nucleotide-binding protein G(t) subunit alpha-2-like {ECO:0000313|Ensembl:ENSPNAP00000000514.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000000514.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000000514.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_017577488.1; XM_017721999.1.
DR AlphaFoldDB; A0A3B4BPX8; -.
DR STRING; 42514.ENSPNAP00000000514; -.
DR Ensembl; ENSPNAT00000013710.1; ENSPNAP00000000514.1; ENSPNAG00000007558.1.
DR GeneID; 108442114; -.
DR CTD; 2780; -.
DR GeneTree; ENSGT00940000158399; -.
DR OMA; ICKPDYM; -.
DR OrthoDB; 2897309at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007188; P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0050908; P:detection of light stimulus involved in visual perception; IEA:Ensembl.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001408; Gprotein_alpha_I.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR PANTHER; PTHR10218:SF68; GUANINE NUCLEOTIDE-BINDING PROTEIN G(T) SUBUNIT ALPHA-2; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR PRINTS; PR00441; GPROTEINAI.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..26
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 354 AA; 39998 MW; EB6E1F7A6B8733F7 CRC64;
MGSGASAEDK EMAKRSKELE KQLQEDADKE AKTVKLLLLG AGESGKSTIV KQMKILHQGG
YTKEEQIAFR AIIYGNILQS ALALIRGMEM LGINYGAPAS QEDGQKLQNL ADSTEDGAMP
PELADVIKRL WKDTGVQAAF ERASEYQLND SAGYYLCDMD RICKPDYIPT EQDVLRSRVK
TTGIIEEQFG CKELHFRMFD VGGQRSERKK WIHCFEGVTC IIFCGALSAY DMVLVEDDEV
NRMHESLHLF NSICNHRFFA TTSIVLFLNK KDLFEEKIKK VHLSICFPEY DGPNTYEDAS
NYIKAQFQDL NMKKGVKEIY AHMTCATDTK NVEIVFNAVT DIIIKENLKD CGLF
//
