ID   A0A3B4BQK1_PYGNA        Unreviewed;       803 AA.
AC   A0A3B4BQK1;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Heterogeneous nuclear ribonucleoprotein U {ECO:0000313|Ensembl:ENSPNAP00000001987.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000001987.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000001987.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_017575696.1; XM_017720207.1.
DR   AlphaFoldDB; A0A3B4BQK1; -.
DR   STRING; 42514.ENSPNAP00000001987; -.
DR   Ensembl; ENSPNAT00000011195.1; ENSPNAP00000001987.1; ENSPNAG00000001055.1.
DR   GeneID; 108440973; -.
DR   CTD; 334490; -.
DR   GeneTree; ENSGT00940000156546; -.
DR   OMA; PHQFQQR; -.
DR   OrthoDB; 5402316at2759; -.
DR   Proteomes; UP000261440; Unplaced.
DR   CDD; cd12884; SPRY_hnRNP; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.10.720.30; SAP domain; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003034; SAP_dom.
DR   InterPro; IPR036361; SAP_dom_sf.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR035778; SPRY_hnRNP_U.
DR   PANTHER; PTHR12381:SF11; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U; 1.
DR   PANTHER; PTHR12381; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER; 1.
DR   Pfam; PF13671; AAA_33; 1.
DR   Pfam; PF02037; SAP; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   SMART; SM00513; SAP; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF68906; SAP domain; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50800; SAP; 1.
PE   4: Predicted;
KW   Methylation {ECO:0000256|ARBA:ARBA00022481};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   DOMAIN          6..40
FT                   /note="SAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50800"
FT   DOMAIN          198..394
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   REGION          39..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          599..710
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          731..768
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        53..94
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..156
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        157..180
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   803 AA;  88126 MW;  363EC6FBA6D0EFD4 CRC64;
     MSTINVKKLK VNELKDELKK RQLSDKGLKA ELMDRLQAAL DAEAQAGGEQ EAEENGAEGD
     GGELEQEFMG EEADADADED AAGESMDADE GENGGASEDA AAGDFDELGQ DDEMAEDEEE
     EEEDGDATVD MDKAFEEDDD EDADKIGDED GEPESQPTEG DADKDISADQ KNKKGVKRRR
     EEHGRAYFEF IEESKYSRAK SPLPPLEEED EEFDDTLVCL DPYNCDLHFK VSRDRYSATS
     LTMESFAYLW AGGRGSYGVD KGKASFEMKV TEKIPVKHVK SKSMDVHDVQ IGWSLANSSL
     LLGEEEHSYA FALKGKKTAN CVTEDYGETF DENDVIGCFV NFEGDEVEIS YSKNGKDLGV
     AFKSSKEALA GRTLFPHVLC HNCAVEFNFG QKEAPYFPQP EGFTLLQQIP VDQRVRGPKG
     PESKKDCEVI VMVGLPGSGK TTWVMKHTEE NPGKYNVLGT DTIVEKMMIN SLKRQNKDTT
     KLTAISQSAP LFLGKFIEIA ARKKRNYILD QTNVSAAAQR RKMCLFAGFQ RKAVVVLPTD
     EAYKERTQKK AETDGKDVPE HAVLKMKGIY TLPEVGDCFC EVTYVELQKE EATKVLEQYK
     EESKSALPPE KKPNQGTPKK GGLPRKRGGK NQFSRGGGPG PRGGRGGFPN RGNFRGLPGP
     RGGFARPPRG ALPPPAFRGG FPSRGSFSRG GAGGMPNRHM APRGAPARGG MGSMAHRGGG
     MNRGRPMNRG NMTRGGGQGG GPSRGNFNQK FRGRGGAQHQ NRGGFGNRNG SFGMNKAQAF
     NQSWQQGFWN QKPWSQQYHP GYY
//