ID A0A3B4BQS9_PYGNA Unreviewed; 277 AA.
AC A0A3B4BQS9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Transcription factor PU.1-like {ECO:0000313|Ensembl:ENSPNAP00000000891.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000000891.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000000891.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR RefSeq; XP_017578343.1; XM_017722854.1.
DR AlphaFoldDB; A0A3B4BQS9; -.
DR STRING; 42514.ENSPNAP00000000891; -.
DR Ensembl; ENSPNAT00000013081.1; ENSPNAP00000000891.1; ENSPNAG00000000474.1.
DR GeneID; 108442687; -.
DR CTD; 751704; -.
DR GeneTree; ENSGT00940000162754; -.
DR OMA; YEDHRWP; -.
DR OrthoDB; 3980839at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0002761; P:regulation of myeloid leukocyte differentiation; IEA:Ensembl.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF174; TRANSCRIPTION FACTOR SPI-B; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019}.
FT DOMAIN 180..263
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 134..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 277 AA; 31747 MW; 410E2FEA0914967D CRC64;
MQCSLSNWKT EISAAGSACL RSPSYRMEGC VISPSSEEMI AYDQVCRPPY DFYPYLSSDP
DGHFESSWDY HTVHAHQSEL EVPQSNYLTE LHPAPHCCVG LESYHPTLDS GLGPLLPGVP
PQFAYVSHPL YQRSTPGHCS TDDEDAVGRS PPFEVSEGEE DHEDQHASTS STMTGNKRKM
RLYQFLLELL RDGDMKDCIW WVDRERGTFQ FSSKHKEALA SRWGMQKGNR KRMTYQKMAR
ALRNYGKTGE VKKVKKKLTY QFSSEVLRRM SAERKYH
//
