ID A0A3B4BS05_PYGNA Unreviewed; 705 AA.
AC A0A3B4BS05;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Semaphorin-4A-like {ECO:0000313|Ensembl:ENSPNAP00000001286.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000001286.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000001286.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR RefSeq; XP_017568604.1; XM_017713115.1.
DR AlphaFoldDB; A0A3B4BS05; -.
DR STRING; 42514.ENSPNAP00000001286; -.
DR Ensembl; ENSPNAT00000012424.1; ENSPNAP00000001286.1; ENSPNAG00000008074.1.
DR GeneID; 108436565; -.
DR GeneTree; ENSGT00940000154870; -.
DR OMA; CICIMIL; -.
DR OrthoDB; 4266123at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0007411; P:axon guidance; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF145; SEMAPHORIN-4A ISOFORM X1-RELATED; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..705
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017353622"
FT TRANSMEM 657..679
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..473
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
SQ SEQUENCE 705 AA; 78186 MW; 4DFE441110C79DA7 CRC64;
MAGVHQVWKI FTLLGYLHVC QSSNTPRTSF FLGSPGRVLS TYKTSDVQNT TALLLSPDAA
TLFVGVKNAV LSLDVSQPHV ITPKNKYDWT PKHGFRCQTS EKNCANFVRI LQFINSTHLY
ACGSFAFKPE DIILTADSLS VSRAAQSAKG VCPYKGSERN TAVFVDGELY TTTTEDYFGS
TPVISRHFSK GRNNLNLDTT FKKLSDPTFI SSSYIPSEGK VLFFFREEAA EYSYTERFFV
SRVAQVCTDD NGGERVLQKS WTTFAKSQLI CQTEKQLPFN LLQDIVMMPP ADDELPDNTR
FYGIFTSQWA LGSSPTAVCA FTLGSIKAAF SGAYKTYTAE TYQREQPNPN SKLGKCGIHN
DTDSTLNLVK KTFLTATSVK SEGNKQLLIT NEVLYSRITA QTVQAASGHI YTVLYLLTET
GLLHKVVLQN NGFHIIEEIQ VFKQPQTVKS ILLSVTKGVV FVGSSEGVIR VPVSNCSFYS
SCAECVLARD PFCGWDLLGK ACIPVSDMKP DLNVSIRQDI ENGNAEEQCK NLTDRSSALV
RKVVSVQLYR LVMLPCYSSS RQAKVSWRFP NHSTLPQSLY LQHEDGSLIF FVTPSTALEY
FCVTEEQGFQ QTAAISLKLQ TSSRSQTSSS CSGLEPIPVP DLYEDTIMHQ KIYYNELVAV
SSLLAICLFV IAVGALLWWR KSHNTDPADP ECLPAHDVGL SLHLK
//
