ID   A0A3B4BT28_PYGNA        Unreviewed;       471 AA.
AC   A0A3B4BT28;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=RAR related orphan receptor B {ECO:0000313|Ensembl:ENSPNAP00000002803.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000002803.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000002803.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC   -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC       {ECO:0000256|RuleBase:RU004334}.
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DR   RefSeq; XP_017572184.1; XM_017716695.1.
DR   AlphaFoldDB; A0A3B4BT28; -.
DR   STRING; 42514.ENSPNAP00000002803; -.
DR   Ensembl; ENSPNAT00000009809.1; ENSPNAP00000002803.1; ENSPNAG00000009139.1.
DR   GeneID; 108438702; -.
DR   CTD; 6096; -.
DR   GeneTree; ENSGT00940000157708; -.
DR   OrthoDB; 3475284at2759; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0004879; F:nuclear receptor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd06968; NR_DBD_ROR; 1.
DR   CDD; cd06939; NR_LBD_ROR_like; 1.
DR   Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR   Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR   InterPro; IPR035500; NHR-like_dom_sf.
DR   InterPro; IPR044101; NR_DBD_ROR.
DR   InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR   InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR   InterPro; IPR003079; ROR_rcpt.
DR   InterPro; IPR001628; Znf_hrmn_rcpt.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   PANTHER; PTHR45805; NUCLEAR HORMONE RECEPTOR HR3-RELATED; 1.
DR   PANTHER; PTHR45805:SF6; NUCLEAR RECEPTOR ROR-BETA; 1.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   Pfam; PF00105; zf-C4; 1.
DR   PRINTS; PR01293; RORNUCRECPTR.
DR   PRINTS; PR00398; STRDHORMONER.
DR   PRINTS; PR00047; STROIDFINGER.
DR   SMART; SM00430; HOLI; 1.
DR   SMART; SM00399; ZnF_C4; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR   SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR   PROSITE; PS51843; NR_LBD; 1.
DR   PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR   PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU004334};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU004334};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU004334};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT   DOMAIN          11..86
FT                   /note="Nuclear receptor"
FT                   /evidence="ECO:0000259|PROSITE:PS51030"
FT   DOMAIN          222..460
FT                   /note="NR LBD"
FT                   /evidence="ECO:0000259|PROSITE:PS51843"
FT   COILED          94..121
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   471 AA;  52988 MW;  548D21909712E876 CRC64;
     MKSDVVAQIE VIPCKICGDK SSGIHYGVIT CEGCKGFFRR SQQNNASYSC PRQRNCLIDR
     TNRNRCQHCR LQKCLALGMS RDAVKFGRMS KKQRDSLYAE VQKHQQRLQE QRQQQQTGEA
     EALARVYSSG LSSGLGSLGH DIGGAYSNGH LIDMPKGQAN GAPAGYYGMD STQPSPDQSG
     LDMAGMKQIK QEPIYDLTPV PNLFPYSSYQ DSQLAPGVSM GELDRIAQNI IKSHLETCQY
     TAEELQQLAW QTHSYEEVKM YQSKSREVLW QQCAIQITHA IQYVVEFAKR ITGFMELCQN
     DQILLLKSGC LEVVLVRMCR AFNPLNNTVL FEGKYGGMQM FKALGCDDLV SAVFDFAKSL
     CSLQLTEEEI ALFSAAVLIS TDRPWLMEPR KVQKLQEKIY FALQHIMQKN HMDEDALAKL
     IGRIPTLAAL CTLHTEELQA FQQLHPETVN VLFPPLYKEL FNPDAASVMP K
//