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Database: UniProt
Entry: A0A3B4BUE3_PYGNA
LinkDB: A0A3B4BUE3_PYGNA
Original site: A0A3B4BUE3_PYGNA 
ID   A0A3B4BUE3_PYGNA        Unreviewed;       271 AA.
AC   A0A3B4BUE3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Syntaxin-1A {ECO:0000256|ARBA:ARBA00040530};
GN   Name=STX1A {ECO:0000313|Ensembl:ENSPNAP00000003257.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000003257.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000003257.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004236}.
CC       Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane
CC       {ECO:0000256|ARBA:ARBA00004143}; Single-pass type IV membrane protein
CC       {ECO:0000256|ARBA:ARBA00004143}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004370}.
CC   -!- SIMILARITY: Belongs to the syntaxin family.
CC       {ECO:0000256|ARBA:ARBA00009063, ECO:0000256|RuleBase:RU003858}.
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DR   AlphaFoldDB; A0A3B4BUE3; -.
DR   Ensembl; ENSPNAT00000009037.1; ENSPNAP00000003257.1; ENSPNAG00000009715.1.
DR   GeneTree; ENSGT01030000234627; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005484; F:SNAP receptor activity; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   CDD; cd15880; SNARE_syntaxin1; 1.
DR   CDD; cd00179; SynN; 1.
DR   Gene3D; 1.20.5.110; -; 1.
DR   Gene3D; 1.20.58.70; -; 1.
DR   InterPro; IPR010989; SNARE.
DR   InterPro; IPR045242; Syntaxin.
DR   InterPro; IPR006012; Syntaxin/epimorphin_CS.
DR   InterPro; IPR006011; Syntaxin_N.
DR   InterPro; IPR000727; T_SNARE_dom.
DR   PANTHER; PTHR19957; SYNTAXIN; 1.
DR   PANTHER; PTHR19957:SF84; SYNTAXIN-1A; 1.
DR   Pfam; PF05739; SNARE; 1.
DR   Pfam; PF00804; Syntaxin; 1.
DR   SMART; SM00503; SynN; 1.
DR   SMART; SM00397; t_SNARE; 1.
DR   SUPFAM; SSF47661; t-snare proteins; 1.
DR   PROSITE; PS00914; SYNTAXIN; 1.
DR   PROSITE; PS50192; T_SNARE; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW   Exocytosis {ECO:0000256|ARBA:ARBA00022483};
KW   Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   TRANSMEM        249..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          175..237
FT                   /note="T-SNARE coiled-coil homology"
FT                   /evidence="ECO:0000259|PROSITE:PS50192"
FT   COILED          51..89
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   271 AA;  30953 MW;  A2BCF913D37E9727 CRC64;
     DSVRESSSHS LAHWVVQQKV EEIRGFIDSL AEKVEEVKRK HSAILAAPNP DEKTKAELEE
     LMTDIKKLAN KVRSKLKSIQ QTIEQEEGQN RSSADLRIRK TQHSTLSRKF VEVMSEYNAT
     QSSYRERCKG RIQRQLEITG RKTTNEELES MLESDNPAIF TSGIIMDSNI TQQAMNEIET
     RHNEIIKLEN SIRELHDMFM DMAMLVESQG EMIDRIEYNV EHAVDYVERA VSDTKKAVKY
     QSKARRKKIM ILICCVVLGI VIASTVGGVL A
//
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