ID A0A3B4BWM0_PYGNA Unreviewed; 394 AA.
AC A0A3B4BWM0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Cytohesin 3 {ECO:0000313|Ensembl:ENSPNAP00000002889.1};
GN Name=CYTH3 {ECO:0000313|Ensembl:ENSPNAP00000002889.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000002889.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000002889.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_017561059.1; XM_017705570.1.
DR AlphaFoldDB; A0A3B4BWM0; -.
DR STRING; 42514.ENSPNAP00000002889; -.
DR Ensembl; ENSPNAT00000009652.1; ENSPNAP00000002889.1; ENSPNAG00000009257.1.
DR GeneID; 108432024; -.
DR CTD; 100002190; -.
DR GeneTree; ENSGT00940000155825; -.
DR OMA; ERDELCN; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0055113; P:epiboly involved in gastrulation with mouth forming second; IEA:Ensembl.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd01252; PH_GRP1-like; 1.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663:SF320; CYTOHESIN-3; 1.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF01369; Sec7; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 54..241
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT DOMAIN 259..375
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT COILED 16..53
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 394 AA; 46032 MW; CBFAC4E2161BDD2B CRC64;
MDEDSRVPED LSLEERDELS NIRRRKKELL DDIERLKFEI AEVMTEIEQL TCMGECKTTQ
RNKQIAIGRK KFNMDPKKGI QFLLDNDLLQ HTPEDIAQFL YKGEGLNKTV IGDYLGERDD
FNIKVLQAFV ELHEFADLNL VQALRQFLWS FRLPGEAQKI DRMMETFASR YCQCNPGVFQ
SSDTCYVLSF AIIMLNTSLH NPNVRDKPTA ERFISMNRGI NEGGDLPEEL LRNLYESIKN
EPFKIPEDDG NDLTHTFFNP DREGWLLKLG GRVKTWKRRW FILTDNCLYY FEYTTDKEPR
GIIPLENLSI REVEEPRKPN CFELYNPSHK GQVIKACKTE ADGRVVEGNH VVYRISAPTP
EEKEEWIKSI KASISRDPFY EMLATRKRRV AAKK
//
