ID A0A3B4BX45_PYGNA Unreviewed; 614 AA.
AC A0A3B4BX45;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 {ECO:0000313|Ensembl:ENSPNAP00000004257.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000004257.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000004257.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_017573893.1; XM_017718404.1.
DR AlphaFoldDB; A0A3B4BX45; -.
DR STRING; 42514.ENSPNAP00000004257; -.
DR Ensembl; ENSPNAT00000007311.1; ENSPNAP00000004257.1; ENSPNAG00000010693.1.
DR GeneID; 108439803; -.
DR CTD; 100005227; -.
DR GeneTree; ENSGT00940000154996; -.
DR OMA; HFFLEGW; -.
DR OrthoDB; 2911036at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR026906; LRR_5.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24373:SF331; LEUCINE-RICH REPEAT AND IG DOMAIN-CONTAINING 4B-RELATED; 1.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF00560; LRR_1; 1.
DR Pfam; PF13306; LRR_5; 1.
DR Pfam; PF13855; LRR_8; 2.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00369; LRR_TYP; 10.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..614
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017432703"
FT TRANSMEM 548..573
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 407..500
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 614 AA; 68537 MW; B34DC17724F10A4C CRC64;
MCVEVTDWRG VYWWVVLLWI VGVAAAGDPP WPCPQRCECL HEILMVNCSS RHLTSVPEGV
HGNTKRLSLA NNRLKMLGRR QFSGLGQLRE LDLSDNMLTM IEVEAFLGLQ NLLTLRLTRN
RLKIIPVGAF SGLSSLRLLD VSENELLVFL DFTFREMASL QKLEASENDL VFISNRAFNG
LLNLQELNLD RCNLTSVPSE ALSQLTGLSR LRFCRVGFTT LPNNSFRRLN RLRELTISHS
PGLDSVAANS LIGLNLTSLT LSYCNLSAVP YAPLHHLVYL RYLDLSYNPI TSIQSNLLGD
LLRLQEFHLV GGSLLRVEPG AFRGLVHFRL LNVSSNRLLT LEETIFHSVG TLEVLRLDGN
PLACDCRMLW VLRRRLRLDF DGQPPSCASP VQVQGRKFQD FTEAELPGLF TCRQARILNR
KPQEVRTDEG HTVLFFCQVD GDPIPSVIWV SPQRTLISTT GRIRVLPNGT LEVRYAQVQD
SGYYRCFASN AAGNDSISVS LRVRGFPASS SRNRSAHFFL EGWSLASTQM PVNGSQGPQP
FPFDVKTLVI AVTMGFLSFL SSVAICFVFM FFWSQSKGQI KHTATIDFVP RSAGAASTGG
GTSMETGRFT MKLI
//
