ID   A0A3B4BYJ9_PYGNA        Unreviewed;       989 AA.
AC   A0A3B4BYJ9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Multimerin-2-like {ECO:0000313|Ensembl:ENSPNAP00000003559.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000003559.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000003559.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR   RefSeq; XP_017558351.1; XM_017702862.1.
DR   AlphaFoldDB; A0A3B4BYJ9; -.
DR   STRING; 42514.ENSPNAP00000003559; -.
DR   Ensembl; ENSPNAT00000008508.1; ENSPNAP00000003559.1; ENSPNAG00000009978.1.
DR   GeneID; 108430395; -.
DR   CTD; 566255; -.
DR   GeneTree; ENSGT01030000234633; -.
DR   OMA; ENRYALE; -.
DR   OrthoDB; 4634169at2759; -.
DR   Proteomes; UP000261440; Unplaced.
DR   Gene3D; 2.60.120.40; -; 1.
DR   InterPro; IPR001073; C1q_dom.
DR   InterPro; IPR011489; EMI_domain.
DR   InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR   PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR   PANTHER; PTHR15427:SF6; MULTIMERIN-2; 1.
DR   Pfam; PF00386; C1q; 1.
DR   Pfam; PF07546; EMI; 1.
DR   SMART; SM00110; C1Q; 1.
DR   SUPFAM; SSF49842; TNF-like; 1.
DR   PROSITE; PS50871; C1Q; 1.
DR   PROSITE; PS51041; EMI; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW   Secreted {ECO:0000256|ARBA:ARBA00022530};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..989
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017292015"
FT   DOMAIN          83..159
FT                   /note="EMI"
FT                   /evidence="ECO:0000259|PROSITE:PS51041"
FT   DOMAIN          856..986
FT                   /note="C1q"
FT                   /evidence="ECO:0000259|PROSITE:PS50871"
FT   REGION          155..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          826..854
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          302..329
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          477..504
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        156..170
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        180..197
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        834..848
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   989 AA;  110386 MW;  16277ECE25C5C365 CRC64;
     MVLTLLMAML LHTAPCHAGL RARDPDVEEE MQALRDSELG AMGTAHFPIP HGHRHHSTAG
     PLQPPLGIPE TPLRESSHQP VRTGNWCAFV HQRVVTMAVL CGTETYTQKS VNPCSKGDPD
     CHISKYQLSS RPVYRQKQKI FTALHWKCCP GHGGHNCQER GRESQAGQEH TGRTHTDISG
     VDNSGDKETD LLEDGSWDDS KVQQPPSGPM FPVQGDIGTG GAVPPPTALH FMDSATLLMA
     HQIFAALMTQ IQPVLDDFNR TLKHLSSEVE DLSMDLQMLR HGQEGHMSNS KQTYTGTIEE
     KLEDSFMQIR QIQAQLDSQQ NQMEQTVQSQ QKLLQYNLTS IKEEIGHHIN KSHEDIQVSL
     QSLSQSVEEI RIGQENLEGL TQEEYAPSAR LSEGQRVPEP GVWEAISRLD KKVLNNTMQL
     SDLSENSKHL KSAAQKLDHC LKNLSTKLEQ VSQSSVIHFT ETGLELEAAK VAALNSVNEL
     SSNLSSQERQ LRELELYLDN IYEQVQRNEP TTTAEACSCK EISESLSLLE LKLANVTDLA
     KKNQYALEDA EAMRGQSHWS MEVDDLHQAL LSVRESLAFE QAKSRTLSGN VSQLKASLLG
     SQQEILGLKE SFGAKAAEIG HLSASFSSLL RDTIRHAEVL EVLLGDEVME FSSWSDTQQK
     ELSIPVLLQK TRLMQEKIET HDNRLTSLRR SSAEKDQMTS DDPVAFSEWG LTEDKERDAE
     DHQVDPFVPG LSTGEDDGDY SVSDFWSLGK EVEELADRIS QLEQQQCNCT AVPGGSVMEL
     QGEVVSLRQA LGDHLRIFQN LFSYTEQLAS SSRSLDLDQV WSMIRRKDRK RNKGQNMKEK
     EESSSMRSKR NTKTGTLYPP VAFVTSLQHR TNTGGMLIPK KVDVNHGNAY QPSSGEFYAP
     QTGLYLFLVT LNFEKGPCLA QLKHGMVPVA SIRQVQVEGG PLSRACLLEL QRGERITLEL
     LKGRLRQGQL NDNTLSGILL FNTEEKDRL
//