ID A0A3B4C3M3_PYGNA Unreviewed; 385 AA.
AC A0A3B4C3M3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Carbonic anhydrase 14 {ECO:0000313|Ensembl:ENSPNAP00000005194.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000005194.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000005194.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC {ECO:0000256|ARBA:ARBA00010718}.
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DR RefSeq; XP_017556351.1; XM_017700862.1.
DR AlphaFoldDB; A0A3B4C3M3; -.
DR STRING; 42514.ENSPNAP00000005194; -.
DR Ensembl; ENSPNAT00000005710.1; ENSPNAP00000005194.1; ENSPNAG00000001753.1.
DR GeneID; 108429241; -.
DR CTD; 23632; -.
DR GeneTree; ENSGT00940000156893; -.
DR OrthoDB; 49814at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004089; F:carbonate dehydratase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002088; P:lens development in camera-type eye; IEA:Ensembl.
DR Gene3D; 3.10.200.10; Alpha carbonic anhydrase; 1.
DR InterPro; IPR001148; CA_dom.
DR InterPro; IPR036398; CA_dom_sf.
DR InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR PANTHER; PTHR18952; CARBONIC ANHYDRASE; 1.
DR PANTHER; PTHR18952:SF84; CARBONIC ANHYDRASE 14; 1.
DR Pfam; PF00194; Carb_anhydrase; 1.
DR SMART; SM01057; Carb_anhydrase; 1.
DR SUPFAM; SSF51069; Carbonic anhydrase; 1.
DR PROSITE; PS51144; ALPHA_CA_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..385
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017188718"
FT TRANSMEM 309..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 35..296
FT /note="Alpha-carbonic anhydrase"
FT /evidence="ECO:0000259|PROSITE:PS51144"
FT REGION 363..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 385 AA; 42491 MW; EEBC67C34D8E11EA CRC64;
MCVWELGRES MDPAWLAATV FLLLWQCVES TRAVKEWTYT GVVGQSEWSE VFPECGGSGQ
SPIDVDTSRT RYDPSLSPVQ PLGYGQYGRE PFTLSNNGHT VEMPLRSWMG VAGLPWQFSA
IQLHLHWGNG VGVATGSEHT IDGRSASAEL HVVHYNSELY ANMSEAKTQA NGLAVLGVLI
EAGGETNQAY TNIFNYLGRI RHAGQKVAIP GFDVQTLLPR DLNRYFRYNG SLTTPPCYQS
VLWTVFAERV RISHSQLLKL ETVLYSTKPG VSQPTLLQDN YRATQPLNHR TVLSSFIPVS
VKIYTDGEIS AIVIGSLCGC IGLATITWFA VKTIRSTSSW DVLPSVRLPP QTRTKDVAKD
LKQDMALRTT SDPGKKEEAV TPPEP
//
