ID   A0A3B4C904_PYGNA        Unreviewed;       725 AA.
AC   A0A3B4C904;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Nucleolar protein 9 {ECO:0000313|Ensembl:ENSPNAP00000006914.1};
GN   Name=NOL9 {ECO:0000313|Ensembl:ENSPNAP00000006914.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000006914.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000006914.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
CC       {ECO:0000256|ARBA:ARBA00011003}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_017576394.1; XM_017720905.1.
DR   RefSeq; XP_017576395.1; XM_017720906.1.
DR   AlphaFoldDB; A0A3B4C904; -.
DR   STRING; 42514.ENSPNAP00000006914; -.
DR   Ensembl; ENSPNAT00000002733.1; ENSPNAP00000006914.1; ENSPNAG00000012851.1.
DR   GeneID; 108441409; -.
DR   CTD; 79707; -.
DR   GeneTree; ENSGT00940000153668; -.
DR   OMA; KEKPYRR; -.
DR   OrthoDB; 5480745at2759; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0051731; F:polynucleotide 5'-hydroxyl-kinase activity; IEA:InterPro.
DR   GO; GO:0000448; P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:Ensembl.
DR   GO; GO:0060216; P:definitive hemopoiesis; IEA:Ensembl.
DR   GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
DR   GO; GO:0031017; P:exocrine pancreas development; IEA:Ensembl.
DR   GO; GO:0001889; P:liver development; IEA:Ensembl.
DR   GO; GO:0061113; P:pancreas morphogenesis; IEA:Ensembl.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR045116; Clp1/Grc3.
DR   InterPro; IPR032319; CLP1_P.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12755; CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P; 1.
DR   PANTHER; PTHR12755:SF3; POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9; 1.
DR   Pfam; PF16575; CLP1_P; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          351..481
FT                   /note="Polyribonucleotide 5'-hydroxyl-kinase Clp1 P-loop"
FT                   /evidence="ECO:0000259|Pfam:PF16575"
FT   REGION          1..47
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          86..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..27
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..107
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   725 AA;  80131 MW;  CC656C44E8F6A8FE CRC64;
     MKVHKVSPRS RNEQRKRHPP KNKWRVHNKK ISNVDPSGLS SSPATAKLEH HLATRQKLKL
     KRLQKVYTKA VDLTLEDNHS VRAKGKVSAP VTLPQAHTNG GTEVEAASDS EDSQEWRSYA
     KSVLQNGMER RGGRENSAPA ASEQLEDEEL PGYHAQHDHV QNHTVLVLQQ GQSLCFRGRC
     LLTCLSGRVE VLGFTIEQGQ QPYPLFSPSS HCPLTITALG DCTPSTKNKK EGRLEAKAIV
     RKYLSSEPRK RLLSEVDSDS CVVLLQPLDT PLTRFLSSFS ELSPLFDINS KELRSQAAVY
     DPALSAVGVT ALRGPCRQGL VTSLSYREAL SNLLSAWEGD FDRCPIVLVC GAKNSGKSTF
     NRHLINSLLN HTASVEYLEC DLGQTEFTPP GCLSLSTVTE PLLGPPFTHQ REPDHMVFYG
     QADCQADLDR YLDSLKTLWR HYSGENPIII NTMGWVKGHG FQLLLDLIRF FSVTHLVQLS
     YGDTPQCHSL TPEFLRSAQG WQTHPPSQPS ITDEPVSHLS ARSHVLLSVH SEFEGAGTSG
     EMRHQRSNEL RDLALLGYFS HLQSSEPGPI RPLHCFTPYQ VPHSAVAIGV THCEVAPNHI
     LYAANASLVG LCCLGEKVSG RGGPVLLSQV PICHCVGLGV LRGVDMARGL YFLVTPVPPA
     ALRQVNCLLL GEIKMPKILF TTQHGVEMEL PYVTTDYSFD ITGAGKLHVF KRRTRTCFVN
     TKTNN
//