ID   A0A3B4CBI8_PYGNA        Unreviewed;       242 AA.
AC   A0A3B4CBI8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Interleukin-1 beta {ECO:0000256|ARBA:ARBA00014702};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000007804.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000007804.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000256|ARBA:ARBA00004514}. Lysosome
CC       {ECO:0000256|ARBA:ARBA00004371}. Secreted, extracellular exosome
CC       {ECO:0000256|ARBA:ARBA00004550}.
CC   -!- SIMILARITY: Belongs to the IL-1 family.
CC       {ECO:0000256|ARBA:ARBA00010448}.
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DR   AlphaFoldDB; A0A3B4CBI8; -.
DR   STRING; 42514.ENSPNAP00000007804; -.
DR   Ensembl; ENSPNAT00000001227.1; ENSPNAP00000007804.1; ENSPNAG00000013513.1.
DR   GeneTree; ENSGT00980000198991; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0005125; F:cytokine activity; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR   Gene3D; 2.80.10.50; -; 1.
DR   InterPro; IPR000975; IL-1_fam.
DR   InterPro; IPR008996; IL1/FGF.
DR   PANTHER; PTHR10078:SF30; INTERLEUKIN-1 BETA; 1.
DR   PANTHER; PTHR10078; INTERLEUKIN-1 FAMILY MEMBER; 1.
DR   Pfam; PF00340; IL1; 1.
DR   SUPFAM; SSF50353; Cytokine; 1.
PE   3: Inferred from homology;
KW   Lysosome {ECO:0000256|ARBA:ARBA00023228}.
SQ   SEQUENCE   242 AA;  27561 MW;  E192CBB2B629E30F CRC64;
     FSRKPHNPFN CGPCDSIKPY SKEEITLRFR MAMVREECLE GEENGVDPAM CEWESDYTEN
     DQELLLVSMN ETSVAVMSGR GCDPENPCNS CGCHGCNLSE VVVVADSCNV TSGKTHCMTR
     MHIVCLSAPI NVYYYTELKQ TFIGKPVVLE LNEINEFLKC TCESQKVVLK SECCDEEKLK
     KVCKDDKEML SFVFYMKTLK DDTKLFESAA HRGWFIETNN HVAMENRPEQ ISGSFYFQQK
     KG
//