ID   A0A3B4CIG7_PYGNA        Unreviewed;       507 AA.
AC   A0A3B4CIG7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Cell division cycle 73 {ECO:0000313|Ensembl:ENSPNAP00000010294.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000010294.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000010294.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the CDC73 family.
CC       {ECO:0000256|ARBA:ARBA00010427}.
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DR   AlphaFoldDB; A0A3B4CIG7; -.
DR   STRING; 42514.ENSPNAP00000010294; -.
DR   Ensembl; ENSPNAT00000016904.1; ENSPNAP00000010294.1; ENSPNAG00000015851.1.
DR   GeneTree; ENSGT00390000001114; -.
DR   OMA; CAFHLKY; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0016593; C:Cdc73/Paf1 complex; IEA:Ensembl.
DR   GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
DR   GO; GO:0034243; P:regulation of transcription elongation by RNA polymerase II; IEA:Ensembl.
DR   GO; GO:0021529; P:spinal cord oligodendrocyte cell differentiation; IEA:Ensembl.
DR   GO; GO:0006368; P:transcription elongation by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 3.40.50.11990; RNA polymerase II accessory factor, Cdc73 C-terminal domain; 1.
DR   InterPro; IPR007852; Cdc73/Parafibromin.
DR   InterPro; IPR031336; CDC73_C.
DR   InterPro; IPR038103; CDC73_C_sf.
DR   InterPro; IPR032041; Cdc73_N.
DR   PANTHER; PTHR12466; CDC73 DOMAIN PROTEIN; 1.
DR   PANTHER; PTHR12466:SF8; PARAFIBROMIN; 1.
DR   Pfam; PF05179; CDC73_C; 1.
DR   Pfam; PF16050; CDC73_N; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT   DOMAIN          1..288
FT                   /note="Paf1 complex subunit Cdc73 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16050"
FT   DOMAIN          333..496
FT                   /note="Cell division control protein 73 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05179"
FT   REGION          250..282
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        259..273
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   507 AA;  58335 MW;  36CD5024F1D48FD0 CRC64;
     MADVLSVLRQ YNIQKKEIIA KGDEVIFGEF SWPKNVKTNY VIWGTGKEGQ PKEYYTLDSI
     LFLLNNVHLP HPSYVRRAAT ENIPVVRRPD RKDLLSYLNG ESSSSTSIDR SAPIEIGLQR
     ATQGMCSLYN YKSDEERVRL DKERLAARLE GHKEGIVQTD QIRSLSEAMS VEKIAAIKAK
     IMAKKRSTIK TDLDDDITLK QRSFVDAEVD VTRDIVSRER VWRTRTTILQ SSGKNFSKNI
     FAILQSVKAR EEGRAPEQRP AQNPTQTDPS IRNKQPVPAA YNRYDQERFK GKEETEGFKI
     DTMGTYHGMT LKSVTVRFRV SQARPPPNQK KGSRTPIIII PAATTSLITM LNAKDLLQDL
     KFVTSEEKKK QGIQRDNEVL LQRRKDLVQP GGSTISVTVP YRVIDQPLKL APQDWDRVVA
     VFVQGPAWQF KGWPWLLPDG SPVDIFAKIR AFHLKYDEVR MDPNVQKWDV TVLELSHHKR
     HLDRPVFLRF WETLDKYMVK HKSHLRF
//