ID A0A3B4CKC9_PYGNA Unreviewed; 648 AA.
AC A0A3B4CKC9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Epsin-1-like {ECO:0000313|Ensembl:ENSPNAP00000011823.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000011823.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000011823.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the epsin family.
CC {ECO:0000256|ARBA:ARBA00010130}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_017570108.1; XM_017714619.1.
DR AlphaFoldDB; A0A3B4CKC9; -.
DR STRING; 42514.ENSPNAP00000011823; -.
DR Ensembl; ENSPNAT00000018924.1; ENSPNAP00000011823.1; ENSPNAG00000017515.1.
DR GeneID; 108437491; -.
DR CTD; 406671; -.
DR GeneTree; ENSGT00940000160411; -.
DR OrthoDB; 1532at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR CDD; cd16990; ENTH_Epsin; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12276:SF48; EPSIN-1; 1.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00726; UIM; 3.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
DR PROSITE; PS50330; UIM; 2.
PE 3: Inferred from homology;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121}.
FT DOMAIN 12..144
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 148..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 247..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..296
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..328
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 462..507
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..541
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 648 AA; 67179 MW; 9E625FFC19E511DF CRC64;
MSTSSLRRQV KNIVHNYSEA EIKVREATSN DPWGPSSSLM SEIADLTYNV VAFSEIMSMV
WKRLNDHGKN WRHVYKAMTL MEYLIKTGSE RVAQQCRENI YAVQTLKDFQ YIDRDGKDQG
VNVREKAKQL VTLLKDEERL REERIHALKT KEKMAQTSSA SSAPSAPGLG GIHSGTEADQ
AWPQSSGEED LQLQLALAMS KEEAEQTSAD PLEDAELRYA LSLSKEAHQE EERLRRGDDL
RLQMAIEESK REKTKPEESA LMELSAADPW GAPAAPSSSG PSPPPSVTPA PAAGPWGPTD
PWGAASPASP PSADPWGEGP PTIAPPPDPW GESSSSRANS DPWASTAVTP PSADPWAPSV
AAAPTSLSGS SDPWAGDGVA PATDALTSDP WSGPPKHTNG TGDPERRGSA AAGGDASGGG
STGSPVPFDL SALGTSLPIR KTPESFLGPN AALVDLDSLV SSKPKPKQTP PTMASSHNPF
LQTQGSSPAP GMAVTPGSTI SSRGVSPTPP PTSNPFGVTP MASISPQPST LGLSQLRTSP
VPPNPMLGHM PPPTLGMVQP GMAMPAMGVP MAAPSMGMGM VQSSPMGMPF SGISPMVPAG
NSLMMGSAGA PQPALVLGGP SGVGGVMGTG GSVGGGGTTG PSTNPFLL
//
