ID A0A3B4CLL1_PYGNA Unreviewed; 656 AA.
AC A0A3B4CLL1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Kelch-like protein 15 {ECO:0000256|ARBA:ARBA00019835};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000011721.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000011721.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_017573717.1; XM_017718228.1.
DR AlphaFoldDB; A0A3B4CLL1; -.
DR STRING; 42514.ENSPNAP00000011721; -.
DR Ensembl; ENSPNAT00000018759.1; ENSPNAP00000011721.1; ENSPNAG00000017414.1.
DR GeneID; 108439687; -.
DR CTD; 80311; -.
DR GeneTree; ENSGT00940000159116; -.
DR OrthoDB; 5472491at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0031463; C:Cul3-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd18454; BACK_KLHL15; 1.
DR CDD; cd18244; BTB_POZ_KLHL15; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR030597; BTB_POZ_KLHL15.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR047030; KLHL15_BACK.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF12; KELCH-LIKE PROTEIN 15; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 5.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 83..150
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 75224 MW; 868A0ACD68FB17DB CRC64;
MSEGPRAAWS KRGCAESHRR EQGKHKQRKC ERPLSTLSVK PPTGQEAAKR CLMAGEVEVY
LSQVHDGSVS SGFRALYEER LLLDVTLLIE EHHFQAHKAL LATQSDYFRV MFTADMRERD
QDKIHMKGLT AAGFGHVLRF MYYGSLELSM PTVQEILQAA MYVQLTEAVE FCCSFLLAKI
CLENCAEVMR LLDDFSVGVE GVQEQLDAFL LENFVPLMAR PDFLSYLSLE KLMAYLDSDQ
LSRFPEIELY EAVQAWLRHD RRRWRHTDAV VQNLRFCLMT PTQVFEKVKT SEFYRYSRQL
RQEVDQALNY FHAVNEQPLA DTKANRIRSV RPQTAVFRGM IGHSMVNSKI LLLHRPKVWW
ELEGPQVPLR PDCLAIVNNF AFLLGGEELG PDGEFHASSK VYRYDPRQNS WLRMADMSVP
RSEFAVGVIG KFIYAVAGRT RDETFYSTER YDIAEDKWEF VDPYPVNKYG HEGTVLNGKL
YITGGITSSS TSKQVCVFDP GREGASEHRT RRTPILTNCW ENKSKMNYAR CFHKMISHNG
KLYVFGGVCV ILRASFESQG CPSTEVYNPE TDEWTILASM PIGRSGHGVA VLDKQIMVLG
GLCYNGHYSD SILTFDPEEN KWKEDEYPRM PCKLDGLQVC SLHFPEYVLE HVRRCS
//
