ID A0A3B4CNP6_PYGNA Unreviewed; 869 AA.
AC A0A3B4CNP6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Semaphorin-4G-like {ECO:0000313|Ensembl:ENSPNAP00000012416.1};
GN Name=SEMA4G {ECO:0000313|Ensembl:ENSPNAP00000012416.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000012416.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000012416.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR RefSeq; XP_017576944.1; XM_017721455.1.
DR AlphaFoldDB; A0A3B4CNP6; -.
DR STRING; 42514.ENSPNAP00000012416; -.
DR Ensembl; ENSPNAT00000019655.1; ENSPNAP00000012416.1; ENSPNAG00000018162.1.
DR GeneID; 108441763; -.
DR CTD; 563785; -.
DR GeneTree; ENSGT00940000157186; -.
DR OMA; SGPYMEY; -.
DR OrthoDB; 4634702at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0007411; P:axon guidance; IEA:UniProt.
DR CDD; cd11262; Sema_4G; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF17; SEMAPHORIN-4G; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..869
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017274046"
FT TRANSMEM 705..731
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..504
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT DOMAIN 573..631
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 654..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 781..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..683
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 787..803
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 869 AA; 97477 MW; 6FE7C60968FB5762 CRC64;
MMSRDVAWLS CLQLLCGMSS LWAYPFRPPL DLDITPRTTV LSNGLWGCRR FSGTALNYST
LLLEEEAGVL YVGARGALYA LQADNISNFS RTIDWEAPED QKQLCLNKGK DNKTECFNHI
RFLQRFNSTH LYTCGTHAFS PLCAYIDDKD FRISSVFEEG RERCPYDPAK GYTGLLIDGQ
IYTASQYEFW SSPDIRRNSP NPTLRTEEAP TRWLYEADFV GSALVRETVN SSVGDDDKIY
FFFTEKSQEH SPYFSHSRVA RVGRVCKSDR GGLLTLQKKW TSFLKARLVC SLPDYEFHFN
VLRSVFVLEG LRTQDTVLYG IFGLEWKNVK ASAICRYSMT DIQQAFDGPY MESQEDTSAK
WTEYSGKVPE PRPGSCITDR LRARGINFST DLPDDVLHFV RRHPLMAKQI LPVGGRPLLF
RRSVDYSKIA VHRVTALDGQ TYHMLFIGTD EGWLQRAVEV KSQLHIIEEL QLFEGPQPVD
SIVISQKQMS VYVGSQSAVV QLPLSTCHRY SSCFDCVLAR DPFCAWDGEE CVEITSHTDR
SNLTQDILNG NEGCENSAAD DLVLHRVRSV MAGDDVLLQC ELSSNLATPQ WTLHGQELQG
YGLNSGYRIG TDGLLVIEAR PDQSGDYSCF ALESGVRVPV VIYTLTIRHD LPPVPPIDMT
HPPHQSGTTH RTAQTSNRSN LTLHPAPAPH PPQLEFLSLR NMEAMYLSLI TILGGLCLVL
TVVLLYVGFC VQTRRGKYSL RAAAQAERKR SGHMELKTIS SQCNGKVDTH DGLLQIVPGE
AQASPNKDLP PAPPLPPPPP NSESEYTNGL SATLPSVLRK MNGNSYVLLR QSDGDTTSPL
YYSFTEELNR ILEKRKHTQL CNKPDESSV
//
