ID A0A3B4CTS5_PYGNA Unreviewed; 441 AA.
AC A0A3B4CTS5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Vav 3 guanine nucleotide exchange factor b {ECO:0000313|Ensembl:ENSPNAP00000014753.1};
GN Name=NTNG1 {ECO:0000313|Ensembl:ENSPNAP00000014753.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000014753.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000014753.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR AlphaFoldDB; A0A3B4CTS5; -.
DR STRING; 42514.ENSPNAP00000014753; -.
DR Ensembl; ENSPNAT00000022751.1; ENSPNAP00000014753.1; ENSPNAG00000020722.1.
DR GeneTree; ENSGT00940000153601; -.
DR OMA; SHAMQHY; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00055; EGF_Lam; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF28; NETRIN-G1; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 1.
DR Pfam; PF00055; Laminin_N; 1.
DR SMART; SM00180; EGF_Lam; 1.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..441
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017406461"
FT DOMAIN 42..293
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 356..391
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 381..390
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 441 AA; 50596 MW; ECBE6943D35109A6 CRC64;
LLLSYFLQTM HWVCAMQHYP ASWGHYDVCK SQVYTEDRLA WHYMACQPEA TDMTKYLRVS
LDPPNITCGD PPEMYCALEN PYMCNNECDA ATEELAHPPE LMFDFEGRNP TTFWQSTSWK
KYPKPLQVNI TLSWNKSIEL TDDIVITFES GRPEQMVLEK SLDFGRTWQP YQFYATDCLD
AFTMEPKAVH ELTQRTLLDI ICTEDYSRGY VWKYDKTVRF EIKDRFALFA GPRLHNMASL
YGQLDTTKNL RDFFTLTDLR IRLLRPATGA TMVDENNLSR YFYAISDIKV QGRCKCNLHA
NSCVFEKGKL SCECEHNTTG PDCSRCKKHY QGRAWSMGSY LPIPKGTANI CKYISITQVC
DNVLLRCQNG GVCHQHQRCQ CPAGFSGVLC ERVQCQGESC QDLNSGQVSH SLQSSGQFLV
ILLVLKLDDG LTTPEPRPQH H
//
