ID   A0A3B4CTX2_PYGNA        Unreviewed;       299 AA.
AC   A0A3B4CTX2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Uncharacterized LOC108437365 {ECO:0000313|Ensembl:ENSPNAP00000014196.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000014196.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000014196.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Acts as a defensive agent. Recognizes blood group fucosylated
CC       oligosaccharides including A, B, H and Lewis B-type antigens. Does not
CC       recognize Lewis A antigen and has low affinity for monovalent haptens.
CC       {ECO:0000256|ARBA:ARBA00002219}.
CC   -!- SUBUNIT: Homotrimer. {ECO:0000256|ARBA:ARBA00011233}.
CC   -!- SIMILARITY: Belongs to the fucolectin family.
CC       {ECO:0000256|ARBA:ARBA00010147}.
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DR   AlphaFoldDB; A0A3B4CTX2; -.
DR   Ensembl; ENSPNAT00000022044.1; ENSPNAP00000014196.1; ENSPNAG00000020621.1.
DR   GeneTree; ENSGT01060000248575; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0042806; F:fucose binding; IEA:UniProt.
DR   GO; GO:0010185; P:regulation of cellular defense response; IEA:UniProt.
DR   GO; GO:0001868; P:regulation of complement activation, lectin pathway; IEA:UniProt.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR006585; FTP1.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   PANTHER; PTHR45713; FTP DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45713:SF8; V-FBPL-RELATED; 1.
DR   Pfam; PF00754; F5_F8_type_C; 2.
DR   SMART; SM00607; FTP; 2.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 2.
PE   3: Inferred from homology;
KW   Lectin {ECO:0000256|ARBA:ARBA00022734}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..299
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017283295"
FT   DOMAIN          23..154
FT                   /note="Fucolectin tachylectin-4 pentraxin-1"
FT                   /evidence="ECO:0000259|SMART:SM00607"
FT   DOMAIN          156..299
FT                   /note="Fucolectin tachylectin-4 pentraxin-1"
FT                   /evidence="ECO:0000259|SMART:SM00607"
SQ   SEQUENCE   299 AA;  32676 MW;  270C03CDDC4E51C2 CRC64;
     MFCLLAVFTA AVFTDASLKG THPKNLALYG KATQSSLIGN PWGALGHAYN AIDGNIDSDY
     NHGSCAATET QENPWWRLDL LDEYTVTSIT ITNRGDCCSD RINGAEIHIG NSLRNNGNIN
     PLLSNLRKAS QVFLPGHNLS LVLCEVEVFG YPTPHGQNVA LGGTATQSSI YSNYFASNAV
     DGNRDGIVSR GSCSMVYNDF SPWWKVDLLK RHKVFSVIIT NRQDAAPEKL FGAEIRIGDT
     LDNNGNNNPI CAVVNISTGD PTKFYECNEM EGQYVNIVIP GRNEYLTLCE VEVYGVPLI
//