ID A0A3B4CV70_PYGNA Unreviewed; 431 AA.
AC A0A3B4CV70;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Forkhead box protein C1-B-like {ECO:0000313|Ensembl:ENSPNAP00000016002.1};
GN Name=FOXC1 {ECO:0000313|Ensembl:ENSPNAP00000016002.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000016002.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000016002.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR AlphaFoldDB; A0A3B4CV70; -.
DR STRING; 42514.ENSPNAP00000016002; -.
DR Ensembl; ENSPNAT00000024371.1; ENSPNAP00000016002.1; ENSPNAG00000022149.1.
DR GeneTree; ENSGT00940000162303; -.
DR OMA; TSWYLNQ; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd20044; FH_FOXC1; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR047391; FOXC1/C2-like_FH.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829:SF401; FORKHEAD BOX C1-A-RELATED; 1.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
FT DOMAIN 68..162
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 68..162
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 168..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 386..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 431 AA; 46891 MW; 367B1E185095967C CRC64;
MQARYSVSSP NSLGVVPYIG GDQTYYRAAG GGAYAGMAAP MSVYSHEQYP ASVARAYGPY
GAPKDMVKPP YSYIALITMA IQNSPDKKIT LNGIYQFIME RFPFYRDNKQ GWQNSIRHNL
SLNECFVKVP RDDKKPGKGS YWTLDPDSYN MFENGSFLRR RRRFKKKDVL KEKEERQVKD
TSTRQQTGQQ QQAREGQQEQ QQPVRIQDIK TENGACTPPQ AVSPALGAVP KIESPDSSSS
SHTQGFSVDN IMTSLRGSPP GPTAELASAY GSPCHQSSAC GGAVTATSNA TYHCNMQAMS
LYAGERASVS VDDALPDYIT TTSTASLGQD SGHPHHSHAH HAHQGRLASW YLNQASELGH
LGATYPSAQQ QNFHAVREMF ESQRIGLNNS PVNGTSSSGG GGGGSSCQMA FPSSQSLYRA
SGAFVYDCSK F
//
