ID   A0A3B4CYP1_PYGNA        Unreviewed;       640 AA.
AC   A0A3B4CYP1;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Fermitin family member 3 {ECO:0000313|Ensembl:ENSPNAP00000016470.1};
GN   Name=FERMT3 {ECO:0000313|Ensembl:ENSPNAP00000016470.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000016470.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000016470.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the kindlin family.
CC       {ECO:0000256|ARBA:ARBA00008052}.
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DR   RefSeq; XP_017553760.1; XM_017698271.1.
DR   RefSeq; XP_017553769.1; XM_017698280.1.
DR   AlphaFoldDB; A0A3B4CYP1; -.
DR   STRING; 42514.ENSPNAP00000016470; -.
DR   Ensembl; ENSPNAT00000038142.1; ENSPNAP00000016470.1; ENSPNAG00000022619.1.
DR   GeneID; 108427786; -.
DR   GeneTree; ENSGT00390000013444; -.
DR   OMA; MYRPTSK; -.
DR   OrthoDB; 5399911at2759; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:InterPro.
DR   CDD; cd13205; FERM_C_fermitin; 1.
DR   CDD; cd17185; FERM_F1_KIND3; 1.
DR   CDD; cd01237; PH_fermitin; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR037843; Kindlin/fermitin.
DR   InterPro; IPR040790; Kindlin_2_N.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR037837; PH_Kindlin/fermitin.
DR   PANTHER; PTHR16160; FERMITIN 2-RELATED; 1.
DR   PANTHER; PTHR16160:SF1; FERMITIN FAMILY HOMOLOG 3; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF18124; Kindlin_2_N; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00295; B41; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|ARBA:ARBA00022889}.
FT   DOMAIN          332..436
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
SQ   SEQUENCE   640 AA;  73363 MW;  8A7746D39C9BFCE6 CRC64;
     MAVWDLSVSV EELGAEAPPL KISVTSDLHI GGVILKVVEK TQISKDWSDH ALWWEQKQQW
     LLKPAWTLDK CGIHADARLC LTPQHKPLQL IMPNGVTLRL RACFSSPVFR TVMGICKLLN
     MRHPEELSLL RPAEEKKKKK QKDEEEVFDI TSAPLPTGSI VKLANGMPAF FTESPQMENV
     YKMLSVSQPA LPPETIAKMY RPTSKVDKAQ VNSRWLDSSR SLLQQGLKEN DKLFLRFKYY
     SFHDLTPQFD AVRLTQLYEQ AKWAILLEEI ECTEEEMMLF AALQYHIGKV STTEQLVASC
     PAMDDLDSAL QCLEVKMEAE TSADDMLETM TAPELHDYLK IFRPKKQTLK KYKQFWFTFK
     DTSISYYKSK EESCKEPIQQ MNLKGCEVAP DVSVAGQKFC IRLLIPEPEG MNEVYLRCDN
     EQQYSKWMAA CRLASKGKTL ADASFSSEVQ SIQSFLAMQR TTPGSKAVQS DDSINTHSLV
     SPRYQKKYKP KQLTPRILEA YQNVAQLSLT DALLKFLQIW QALPDFGISY FVVRFKGCRK
     DEVMGIANNR LIRIDMNVEE VVKTWRYNTM RQWNVNWDIK QVAIEFNGNV NIAFSCVTAD
     CKIVHEYIGG YIFMSTRNRE QNDTLNEELF HKLTGGHDAI
//