ID   A0A3B4D2X6_PYGNA        Unreviewed;      1232 AA.
AC   A0A3B4D2X6;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000017868.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000017868.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123, ECO:0000256|PIRNR:PIRNR005719}.
CC   -!- SIMILARITY: Belongs to the SMC family. SMC1 subfamily.
CC       {ECO:0000256|ARBA:ARBA00005597}.
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DR   RefSeq; XP_017553690.1; XM_017698201.1.
DR   AlphaFoldDB; A0A3B4D2X6; -.
DR   STRING; 42514.ENSPNAP00000017868; -.
DR   Ensembl; ENSPNAT00000026837.1; ENSPNAP00000017868.1; ENSPNAG00000024270.1.
DR   GeneID; 108427751; -.
DR   GeneTree; ENSGT00940000155614; -.
DR   OMA; SYIRDHT; -.
DR   OrthoDB; 231904at2759; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0008278; C:cohesin complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0048703; P:embryonic viscerocranium morphogenesis; IEA:Ensembl.
DR   GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR   CDD; cd03275; ABC_SMC1_euk; 2.
DR   Gene3D; 1.20.1060.20; -; 1.
DR   Gene3D; 3.30.70.1620; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR024704; SMC.
DR   InterPro; IPR028468; Smc1_ABC.
DR   InterPro; IPR010935; SMC_hinge.
DR   InterPro; IPR036277; SMC_hinge_sf.
DR   PANTHER; PTHR18937:SF170; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1A; 1.
DR   PANTHER; PTHR18937; STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; 1.
DR   Pfam; PF06470; SMC_hinge; 1.
DR   Pfam; PF02463; SMC_N; 2.
DR   PIRSF; PIRSF005719; SMC; 1.
DR   SMART; SM00968; SMC_hinge; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF75553; Smc hinge domain; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005719}.
FT   DOMAIN          513..629
FT                   /note="SMC hinge"
FT                   /evidence="ECO:0000259|SMART:SM00968"
FT   REGION          940..969
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          161..490
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          664..711
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          748..925
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          996..1065
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        949..969
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1232 AA;  143195 MW;  47E704A5DBD549AD CRC64;
     MGYLKLIEIE NFKSYKGRQI IGPFHKFTAI IGPNGSGKSN LMDAISFVLA EKTSNLRVKT
     LKDLIHGAPV GKPAANRAYV SMVYQEDNGE ERNFTRVIIG SSSEYRINNK VVGLPDYSEA
     LEKLGILIKA RNFLVFQGAV ESIAMKNPKE RTALFEEISR SGELAQEYDR CKKEMVKAEE
     DTQFNYHRKK NIAAERKEAK QEKEEAERYQ RLKDEVVRAN VQLQLFKLYH NESEIEKLNR
     ELAQRNKEIE KDRKRMDRVE EELKDKKKEL GRMMREQQAV EKEIKEKDAE LNQKRPQYIK
     AKENTAHKIK KLEAARKSLQ NAQKCYKKRK ADMDELDREQ KAVEMARQEF EERMEEEAQS
     QGQDLQLEEN QVKAYHRLKE EASKRAATLA QELEKFNRDQ KADQDRLDLE ERKKVETEAK
     IKQKIREIEE NQKRIEKLED YIATSRQSLD EQKRMEEELT EEVEQAKRRI DEINMELNQV
     MEQLGDARID RQENSRQQRK AEIMESIKRL YPGSVYGRLI DLCQPTQKKY QIAVTKVLGK
     NMDAIIVDSE KTGRDCIQYI KEQRGEPETF LPLDYLEVKP TDEKLRELRG AKLVIDVIRY
     EPPQIKKALQ YACGNALVCE NVEDARRIAF GGPYRHKTVA LDGTLFQKSG VISGGASDLK
     AKARRWDEKA VDKLKDRKEK LTDELKEQMK AKRKEAELRQ VQSQAHGLQM RLKYSQSDLE
     QTKTRHLSLN MQEKSKLESE LANFGPRIND IKRIIQSRER DMKELKDRMN LVEDEVFLEF
     CKEIGVRNIR EFEEEKVKRQ NEIAKKRLEF ETQKTRLAIQ LDYEKNQLKE DQEKVVMWEQ
     TVKKDENEIE RLKKEEQRHM KIIDETMAQL QDLKNQHLTK KSEVNDKNHE MEEIRKKLGS
     ANKELTQLQK EVTAIETKSE QKRSDRHNLL QACKMQDIKL PLRSGTMDDI SQEEGSSQEE
     SLSSSQKTSS SVLAKEALIE IDYSSLSDDL KDSLSEEEIK GEMNTLQQRL NEQQSILQRI
     SAPNMKAMEK LESVRDKFQE TSDEFEAARK RAKKAKQAFE QIKKERFDRF NACFESVATN
     IDEIYKALSR NSSAQAFLGP ENPEEPYLDG INYNCVAPGK RFRPMDNLSG GEKTVAALAL
     LFAIHSYKPA PFFVLDEIDA ALDNTNIGKV ANYIKDQSIQ NFQAIVISLK EEFYTKADSL
     IGVYPEQGDC VISKVLTFDL SQYPDANPNP NE
//