ID   A0A3B4D8P9_PYGNA        Unreviewed;       982 AA.
AC   A0A3B4D8P9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=B30.2/SPRY domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000019334.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000019334.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4D8P9; -.
DR   STRING; 42514.ENSPNAP00000019334; -.
DR   Ensembl; ENSPNAT00000029083.1; ENSPNAP00000019334.1; ENSPNAG00000006136.1.
DR   GeneTree; ENSGT01100000263529; -.
DR   OMA; YLCSGWS; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd16040; SPRY_PRY_SNTX; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   Pfam; PF15227; zf-C3HC4_4; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 2.
DR   SMART; SM00589; PRY; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50837; NACHT; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..982
FT                   /note="B30.2/SPRY domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017295159"
FT   DOMAIN          25..68
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          180..314
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   DOMAIN          786..982
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
SQ   SEQUENCE   982 AA;  112547 MW;  EC268884C382B662 CRC64;
     MLCSHLHFLC LSWRMDAQLQ DQSRCGLGHH LLTDPVSITC GHSFCKQCIS CFWEPLAASE
     DFVCPRCRKR FRTHPVLHPY NVSMEQDSYQ PADDNLHEVL EKHKTSIKKK YETLFEGIQI
     PENKTLLNRV YTQLYIIEGE SKGVNEEHEV LQKSLSRKNL QKNPINCSDI FKLLQDKKLR
     TVLTKGIAGI GKTVSAQKFI LDWTEGKANQ DVHFMFVLPF RELNLIKDDQ YSFHGLLCDF
     YPELKDLDPK IYDQYKVVFI FDGLDESRIP LSFSQGEKVS DTTVTSPVGV LLTNLIKGEL
     LPSALIWITS RPAAASQIPS QCINRVTEIQ GFSDPQKEEY FRKRISDQDQ AKRIISHIKT
     ARSLHIMCHI PVFCWISATV LQQVMKHNRE IPKTLTEMYS HFLLTQANMK NEKYEEKDER
     DPKNLLESNR TILLKLAELA FKQLMKGNVM FYEEDLRESN IDVTEASVYS GIFTEIFREE
     CVLYQRKVYC FVHLTFQEFL AAVYVFHCYE SRNIRNVTLD ELLKGVVDKA VESQNGHLDL
     FLRFLLGLSL ESNQRLLRGL LISPQSSSEK TIEYIKELIK GYEQYPFLTD GSLSTERSIN
     LFLCLSEMND QSLSRELQHY LKSNKHSEEK FSPGHCSALA YMLLLSEEVL DELDLKKYNT
     SEEGYRRLIP AVTVCRKALL ALCNLTTNSC EKLGSTLQSA NGPLEELDLG VELLSAGLRS
     SHCKLEILRL SGCMVTNEGC SSLASALKSN PSHLRELDLT YNHPGESGVK LLHDLLKDPH
     CKLEILQVEC GGKIRMKPGR KKYACCLNLD PNTAHRRLCL SEGNRKVQSV EKDQPYLDHP
     DRFDHYYQVL SVESLTGRCY WEAEWTGTEA DIAMTYRGIR RKGCNEECWF GFSDQSWILY
     CSDNSYSVWH NSKKINVLAP PSRSNRVGVY LDWAAGTLSF YSISPSTHTL THLHTFSSSF
     TEPLYAGFGV DFNSSLYMCE VE
//