ID   A0A3B4DC83_PYGNA        Unreviewed;       355 AA.
AC   A0A3B4DC83;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=IRG-type G domain-containing protein {ECO:0000259|PROSITE:PS51716};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000021063.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000021063.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC       superfamily. IRG family. {ECO:0000256|ARBA:ARBA00005429}.
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DR   AlphaFoldDB; A0A3B4DC83; -.
DR   Ensembl; ENSPNAT00000032062.1; ENSPNAP00000021063.1; ENSPNAG00000028650.1.
DR   GeneTree; ENSGT00950000183007; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030385; G_IRG_dom.
DR   InterPro; IPR007743; Immunity-related_GTPase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR32341; INTERFERON-INDUCIBLE GTPASE; 1.
DR   PANTHER; PTHR32341:SF10; INTERFERON-INDUCIBLE GTPASE 5; 1.
DR   Pfam; PF05049; IIGP; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51716; G_IRG; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          30..202
FT                   /note="IRG-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51716"
SQ   SEQUENCE   355 AA;  38461 MW;  A20B7922E21411E4 CRC64;
     HETILLKNLF PHTKSQNLHS PTNIEHLPKV SLSVAVTGES GAGKSTFINA FRNLDDEDEG
     AAETGVTQTT TEPTPYEHPT VSNVVFWDLA GVGTPNFQAK TYDFFLNISS ERFRGNDSML
     PIPAVFGRKA GYTLDRLPVH RRALILQVKK IKGTLTEKKL SKIRRNCEEN LTDLGDSKVF
     LINCQDLTAF DFEELVETLN SELPQFMQDA LVLSVPVSSV AILEEKVKIV EKVILGVATV
     SGGIAAVPVP GLSFACDTAI VGSFFTTCYH IFGLDDKSLK KLSERVNEPD LKNLDKSPLL
     KELAQTSAVR MGASAVGEFL CSLIPVAGSA AAAAISFTTT RALNVAWLLV PDGLV
//