ID A0A3B4DD52_PYGNA Unreviewed; 178 AA.
AC A0A3B4DD52;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Troponin I, fast skeletal muscle {ECO:0000256|ARBA:ARBA00039349};
DE AltName: Full=Troponin I, fast-twitch isoform {ECO:0000256|ARBA:ARBA00042462};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000021378.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000021378.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Troponin I is the inhibitory subunit of troponin, the thin
CC filament regulatory complex which confers calcium-sensitivity to
CC striated muscle actomyosin ATPase activity.
CC {ECO:0000256|ARBA:ARBA00001988}.
CC -!- SUBUNIT: Binds to actin and tropomyosin.
CC {ECO:0000256|ARBA:ARBA00038767}.
CC -!- SIMILARITY: Belongs to the troponin I family.
CC {ECO:0000256|ARBA:ARBA00009930}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_017555501.1; XM_017700012.1.
DR AlphaFoldDB; A0A3B4DD52; -.
DR STRING; 42514.ENSPNAP00000021378; -.
DR Ensembl; ENSPNAT00000032627.1; ENSPNAP00000021378.1; ENSPNAG00000006788.1.
DR GeneID; 108428757; -.
DR GeneTree; ENSGT01030000234588; -.
DR OMA; RRCESHA; -.
DR OrthoDB; 2882372at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005861; C:troponin complex; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.350; -; 1.
DR Gene3D; 6.10.250.180; -; 1.
DR InterPro; IPR001978; Troponin.
DR InterPro; IPR038077; Troponin_sf.
DR PANTHER; PTHR13738; TROPONIN I; 1.
DR PANTHER; PTHR13738:SF15; TROPONIN I, FAST SKELETAL MUSCLE; 1.
DR Pfam; PF00992; Troponin; 1.
DR SUPFAM; SSF90250; Troponin coil-coiled subunits; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Muscle protein {ECO:0000256|ARBA:ARBA00023179}.
FT COILED 54..102
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 178 AA; 20427 MW; ABC497ED0EB640FC CRC64;
MSEKKMSSSR KHHLKSLMLS IAKGLLEVEA KEKESERTRY MADICPPLSL PGGVQALQEL
CRELHHKIDV TDEERYDLAS KVDKSSKEIE DLKIKVQDLK GKFKKPALRK VRLSADQMLQ
ALLGSKHKVS LDLRANLKQV KKEVKEEDKE LRDVGDWRKN IEDKAGMDGR KKMFESEA
//
