ID   A0A3B4DDX9_PYGNA        Unreviewed;       920 AA.
AC   A0A3B4DDX9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Nuclear factor of activated T-cells, cytoplasmic 1-like {ECO:0000313|Ensembl:ENSPNAP00000021261.1};
GN   Name=NFATC1 {ECO:0000313|Ensembl:ENSPNAP00000021261.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000021261.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000021261.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_017566853.1; XM_017711364.1.
DR   AlphaFoldDB; A0A3B4DDX9; -.
DR   STRING; 42514.ENSPNAP00000021261; -.
DR   Ensembl; ENSPNAT00000040461.1; ENSPNAP00000021261.1; ENSPNAG00000007025.1.
DR   GeneID; 108435486; -.
DR   GeneTree; ENSGT00940000157616; -.
DR   OrthoDB; 5405363at2759; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR   GO; GO:0060429; P:epithelium development; IEA:UniProt.
DR   CDD; cd07881; RHD-n_NFAT; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002909; IPT_dom.
DR   InterPro; IPR008366; NFAT.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR032397; RHD_dimer.
DR   InterPro; IPR011539; RHD_DNA_bind_dom.
DR   InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR   PANTHER; PTHR12533; NFAT; 1.
DR   PANTHER; PTHR12533:SF5; NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 1; 1.
DR   Pfam; PF16179; RHD_dimer; 1.
DR   Pfam; PF00554; RHD_DNA_bind; 1.
DR   PRINTS; PR01789; NUCFACTORATC.
DR   SMART; SM00429; IPT; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 1.
DR   PROSITE; PS50254; REL_2; 1.
PE   4: Predicted;
FT   DOMAIN          408..590
FT                   /note="RHD"
FT                   /evidence="ECO:0000259|PROSITE:PS50254"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          211..297
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          339..358
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          777..892
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        225..259
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        275..297
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        777..851
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        866..892
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   920 AA;  99326 MW;  C013A0EC16C84143 CRC64;
     MPATGCLRAD SRGDSRQQQQ PCDGSGGKRR GSELSCSAEA SMKSAEEEAF SYTPNVSLSL
     PLGMGNPCLA SQYHNLQTSP VISVSSCHQA SYGLHENAMG PGYYLSHGLR PNGAPPLESP
     RIEITTYGQM SEEEVEEIGS VDPMAKRVNI VTLTLPSIDG YRDPSCLSPA SSLSSRSCNS
     EASYESGFYN YDNSPQNSPW QSPCVSPKGS SSLLSCPHAP GSVPSPNHSP STSPHATVAN
     DDSWTGAAPR NSRPSSPICS AGSHGKRKYS FNGAPYRQPS YSPNQSPGAS PQGSPRLSVA
     EETWLGTTTN QYTNSAIVAA INALSTDGLA DLGDVPPKSR KTNLEHSPAM SLKVEPGGDD
     MAVSTDLCQE DYSSTNRLPF KKESYCPGFL DVPPHPYSWP KPKPYISPSL PALDWQLPSC
     SGPYSLQIEV QPKSHHRAHY ETEGSRGAVK ALSGGHPVVQ LYGYMESEPL TLQLFIGTAD
     DRLLRPHAFY QVHRITGKTV STASHEAMQS NTKVLEIPLL PENNMRAIID CAGILKLRNS
     DIELRKGETD IGRKNTRVRM VFRVHINQPN GRTVSLQVAS NPIECSQRSA QELPLVEKQS
     LDSYPATGGK RMLLSGHNFL ADSKVMFVEK AQDGHHVWET EAKIDKDSLK PTSLVVEIPP
     YRNQRIASAV PVSFYVCNGK RKRSHYQRFT YLPPNVPMIK TEPTDDYETQ GAPRMPMHSK
     PFYSQQRLPP MMPLSDTDPC MVGGYSPCPP CPAAMPCSSP GSSPKLHDLS PIPFPKCLSS
     SPTHSTMPGN VASLQDTPTH PSLALPSSPD HTSLTMPHPQ GSPHLSSPSY HPLYPSSSPS
     SSPTSHPSTP GAAAESPYLP PFGSAQPRGS PSSLLAEDSS SPALSVTIKQ EPQELDQMYL
     DDVNEIIRND LSSTSAHGHS
//