ID A0A3B4DEW9_PYGNA Unreviewed; 425 AA.
AC A0A3B4DEW9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Ankyrin repeat and SOCS box containing 4 {ECO:0000313|Ensembl:ENSPNAP00000022050.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000022050.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000022050.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR RefSeq; XP_017548344.1; XM_017692855.1.
DR AlphaFoldDB; A0A3B4DEW9; -.
DR STRING; 42514.ENSPNAP00000022050; -.
DR Ensembl; ENSPNAT00000033894.1; ENSPNAP00000022050.1; ENSPNAG00000029289.1.
DR GeneID; 108424675; -.
DR CTD; 51666; -.
DR GeneTree; ENSGT00940000158874; -.
DR OMA; PIQYVLK; -.
DR OrthoDB; 5304250at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03723; SOCS_ASB4_ASB18; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24118:SF99; CHARON; 1.
DR PANTHER; PTHR24118; POTE ANKYRIN DOMAIN; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT REPEAT 105..137
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 138..170
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 173..205
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 250..282
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 378..416
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 425 AA; 47897 MW; FB3F5ACAAFF895B8 CRC64;
MTEARASRRS EAVQQLKSRF LEALKRNDAA EVEKFLRTTN IDIDTVLDVK DTSMVLASYK
QGYWLPGYKL ESSWAMGIHV CMMYNALESA LVLLQRGAAV NRKPNGKTPL HVACEVSHTD
CVNLLLNWGA KVNSVSLSGH TPLHYCITQE SVDCAKQLIL RGANVNAESH NSDEDTPLHT
AARFGISELV ALYAAHGANV DAVNARMETP LITAAFWAMD TREQTYSEDH HLVCRMLLDY
GANPNLQEED KKTALHKASW NCDHVLIQVL LEGGANPSIM DVNGCAALQY VLKVMQFRPL
SIPERCFQLL LNYGAVRVYP KQFHKVLQNC YDYPRAVEVM ANSYEHLMHT KKWRAAIPDA
TYERHRTFYD SLFAVCTNNP RTLQHLARCT IRIAMHGCCE TGIQQIPLPP PIRRYLLLEP
VGIIF
//
