ID A0A3B4DSL8_PYGNA Unreviewed; 644 AA.
AC A0A3B4DSL8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=E3 ubiquitin/ISG15 ligase TRIM25-like {ECO:0000313|Ensembl:ENSPNAP00000026111.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000026111.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000026111.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_017552257.1; XM_017696768.1.
DR RefSeq; XP_017552258.1; XM_017696769.1.
DR RefSeq; XP_017552260.1; XM_017696771.1.
DR RefSeq; XP_017552261.1; XM_017696772.1.
DR STRING; 42514.ENSPNAP00000026111; -.
DR Ensembl; ENSPNAT00000005932.1; ENSPNAP00000026111.1; ENSPNAG00000011380.1.
DR Ensembl; ENSPNAT00000005942.1; ENSPNAP00000026105.1; ENSPNAG00000011380.1.
DR GeneID; 108426939; -.
DR CTD; 767638; -.
DR GeneTree; ENSGT00940000162978; -.
DR OrthoDB; 4020353at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR CDD; cd16040; SPRY_PRY_SNTX; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF36; E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 13..56
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 134..174
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 450..644
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 80..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 175..202
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 88..104
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..392
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 644 AA; 72033 MW; 2036F71D65FBBA3D CRC64;
MATYRCCPEE FSCPVCLEIL CDPATLACGH TYCLQCIRKH WDKAAAKGIY SCPQCRQVFK
PRPTLGRNNM LMEAMKKLRV HEQDKPPSPV HSSLTSSAAV SVDPSSQPAP LDVPEEAAEG
VPVQGGLYPQ LPSTSPKLCP LHQQVLEFYC CDDKKSVCDE CSLLEHKGHR VVRPDEEKEE
KRQELEQKKE MVQKSIQARE KVIQTLPQVF QAHKNAIQGL QRDSLETFAD VVKSVELMSS
QVMELLQTYE ASSYNRTEAH RYRLQQEISQ LCKQKEELNR LANTQDSIQF LNDLVIAGTV
GQVENAQLEI SHPESVEAGI RSALGTFRER LNDLCKGSLA SIFRAVNDAE ARASATNAQA
SETGPVPNDL QVASQKTAPE MISSNSKPID KTSHSAAHQH PPHPPTTAHP DPALIASSSN
RKPEDKTRNS AKREHPPAAT APPVKETATF NTANPVPKTR DEMIKFRFEP TMDPNSAYRH
IRLSEGDRKA TLRAENQNYP EHADRFLYWR QVMCREPLAG SPYYWEVEWT GQKMTIGVAY
KDMARSAADD SSRLGHNEHS WSLYWSGTGF SLWHAGKETT LSAPKARHIG VYIDQQAGIL
AFYRVSQNQA HQICCVETEF SAPLYPGFRF WSGVGSNITL CHLD
//
