ID A0A3B4DSX6_PYGNA Unreviewed; 858 AA.
AC A0A3B4DSX6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Transforming growth factor beta receptor 3 {ECO:0000313|Ensembl:ENSPNAP00000026074.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000026074.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000026074.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_017571060.1; XM_017715571.1.
DR AlphaFoldDB; A0A3B4DSX6; -.
DR STRING; 42514.ENSPNAP00000026074; -.
DR Ensembl; ENSPNAT00000006014.1; ENSPNAP00000026074.1; ENSPNAG00000001688.1.
DR GeneID; 108438048; -.
DR CTD; 7049; -.
DR GeneTree; ENSGT00530000063861; -.
DR OMA; VPQRECV; -.
DR OrthoDB; 2949260at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0061053; P:somite development; IEA:Ensembl.
DR GO; GO:0002040; P:sprouting angiogenesis; IEA:Ensembl.
DR Gene3D; 2.60.40.4100; Zona pellucida, ZP-C domain; 1.
DR Gene3D; 2.60.40.3210; Zona pellucida, ZP-N domain; 1.
DR InterPro; IPR042235; ZP-C.
DR InterPro; IPR001507; ZP_dom.
DR InterPro; IPR017977; ZP_dom_CS.
DR PANTHER; PTHR14002; ENDOGLIN/TGF-BETA RECEPTOR TYPE III; 1.
DR PANTHER; PTHR14002:SF30; TRANSFORMING GROWTH FACTOR BETA RECEPTOR III; 1.
DR Pfam; PF00100; Zona_pellucida; 1.
DR SMART; SM00241; ZP; 1.
DR PROSITE; PS00682; ZP_1; 1.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..858
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017266492"
FT TRANSMEM 794..816
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 434..721
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
FT REGION 375..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 748..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 827..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 384..415
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 858 AA; 93991 MW; 334F852A47DF64D7 CRC64;
MAHRRPIAVL LFALYSVASA GPLSRSPCEL LPVGASHPVQ AFLKSFTAQS GCASRGTTSL
PQEVHIINLR SSSPEGTGER PAEVALHLRP IQSLSVHHKP LVFLLNSPQP VLWKLHTEKL
VPGVRRIFHV SQGSDVQFEG NFSLSCEVQT ETLPHGNEHL LSWAQRRYHA VTSFSELKMA
HDVYIKVGED PVFSDTCKID NKFLSLNYLA SYVEPQTSTG CVLSGPDPQQ EVHVIELQAP
NSSSAFQVDV TVDLRPLEGE IPLHRDVVLL LRCEKSVNWV IEAHSIVGKL RIVTSDSVSL
SASTERLMQV SKTVKQKLPA GAQALIQWAQ ENGYSPVTSY TSTAVANVFN LCLKEADMVD
PLESMFPPEL SILQKGNPHP LPSARDAPAR PSLPFPFPPP SDHGLPFPLL PPSLEEPQGP
EEQRGALTAL LSVRCEESRM VVSIDKESLQ ANGITKANIT LQDPRCKATS NSTHYTLETP
LTGCQTTKYP SHSSPVVLYI NSIVISYSEV RDGSGWPLDD EDLESGDVLF PGYPDSPERT
ALETGHRSTI IFNCTYRKDQ DAAGESHRLG FGRLPKEPVD NVTFSMELFT TNLFRYPPLN
SFLTISENKP IFVEISATKT DPDLGFMIQS CLISPDSNPL VPSMYMIIEN ICPTDDSVLY
YPQKVDFPVP HAQMDRKRFS FTFKSKFKVS LLFLHCEMAL CSKMPSNHQG LPKCMLPDEA
CTSVSFETII KMMMNTKTST KPLVVVLDND SGSVNPEDKS TKTPVPTTHK PPPLLPNAPG
DAESFMYVLD TPTVVGIAFA AFVIGALLTG ALWFIYSHTG YSESKQQVVQ SPPASENSSA
AHSIGSTQST PCSSSSNA
//
