ID   A0A3B4DV86_PYGNA        Unreviewed;       360 AA.
AC   A0A3B4DV86;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Immunity-related GTPase family, e4 {ECO:0000313|Ensembl:ENSPNAP00000027360.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000027360.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000027360.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TRAFAC class dynamin-like GTPase
CC       superfamily. IRG family. {ECO:0000256|ARBA:ARBA00005429}.
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DR   AlphaFoldDB; A0A3B4DV86; -.
DR   Ensembl; ENSPNAT00000002757.1; ENSPNAP00000027360.1; ENSPNAG00000012863.1.
DR   GeneTree; ENSGT00950000183007; -.
DR   OMA; KFQPHEY; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0098542; P:defense response to other organism; IEA:UniProt.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR030385; G_IRG_dom.
DR   InterPro; IPR007743; Immunity-related_GTPase-like.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR32341; INTERFERON-INDUCIBLE GTPASE; 1.
DR   PANTHER; PTHR32341:SF10; INTERFERON-INDUCIBLE GTPASE 5; 1.
DR   Pfam; PF05049; IIGP; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51716; G_IRG; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          25..209
FT                   /note="IRG-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51716"
FT   REGION          42..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   360 AA;  39684 MW;  5DCD42C63AC7A351 CRC64;
     MASGQSTLEG ATRRAQEQAE RLFNVSLSVA VTGDTGTGKS TFIKGIRGRD DDDNDAAETG
     VTEATTEPTS YKCHPTMPNV KFWDLPGTGA PNFKAKNYLK QVQFDRYDFF IIISSERFRE
     NDIMLAKKIQ KRKKLFYFVR SKIDNDIRAE QRKKGFNKDK MLLKIRRNLF LISSMNLSKF
     DFEQLVATLM SELPKLKCQA LLQSLPVSSL AILEEKVRMF KKAVGAVALL SGGVAAAPVP
     GLSFACDTSI LVSFFTRCYY SFGLDDKSLD KLSERVNKPH LKSLITSPLV LGLASKSAVR
     LQLSAIAGSA LVKILCKLVP GVGNAAAGVI SFTLTFTLLK RGLKDLADSA RTMLREAELE
//