ID A0A3B4DX66_PYGNA Unreviewed; 414 AA.
AC A0A3B4DX66;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Arrestin domain-containing protein 3 {ECO:0000256|ARBA:ARBA00041132};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000027651.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000027651.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm
CC {ECO:0000256|ARBA:ARBA00004496}. Early endosome
CC {ECO:0000256|ARBA:ARBA00004412}. Endosome
CC {ECO:0000256|ARBA:ARBA00004177}. Lysosome
CC {ECO:0000256|ARBA:ARBA00004371}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the arrestin family.
CC {ECO:0000256|ARBA:ARBA00005298}.
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DR RefSeq; XP_017551079.1; XM_017695590.1.
DR AlphaFoldDB; A0A3B4DX66; -.
DR STRING; 42514.ENSPNAP00000027651; -.
DR Ensembl; ENSPNAT00000002008.1; ENSPNAP00000027651.1; ENSPNAG00000002600.1.
DR GeneID; 108426240; -.
DR CTD; 566685; -.
DR GeneTree; ENSGT00940000155411; -.
DR OMA; IHAGRHE; -.
DR OrthoDB; 22053at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.640; -; 2.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011021; Arrestin-like_N.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR11188; ARRESTIN DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11188:SF49; ARRESTIN DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00339; Arrestin_N; 1.
DR SMART; SM01017; Arrestin_C; 1.
DR SUPFAM; SSF81296; E set domains; 2.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 187..314
FT /note="Arrestin C-terminal-like"
FT /evidence="ECO:0000259|SMART:SM01017"
FT REGION 385..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..414
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 414 AA; 46404 MW; 8CC75D5256F8C4EF CRC64;
MVLGKVKSFV VSYDCLNDSN VPVFSSGDCV SGRVVIEVTG EIRVKSLKIH AKGFAKVRWT
ESRNAGSNTA YTQNYTEEVE YLNHRDILIG HERDDDNSEE GLTTIHSGRH EYAFSFELPQ
TPLATSFEGK HGSVRYWVKA ELHRPWLLPM KSKKEFTVFE HIDINTPLLL SPQAGTKDKT
LCCWFCTSGP ISLSAKIERK GYTPGESIQI FAEIENCSSR MVVPKAAIYQ TQTFFAKGKM
KEIKQLVANL RGESLSSGKT ETWNGKMLKI PPVSPSILDC SIIRVEYSLM VYVDIPGAMN
LSLNLPLVIG TIPLHPFGSR TSSVSSQCSM TMSWLGMSLP ERPEAPPAYA EVVTEEQRQS
CLEVSSGRED FDGPLFAYIQ EFRFQPPPPY SEIDPNPDQA RRTEERRPDT CPSR
//
