ID A0A3B4DYS9_PYGNA Unreviewed; 446 AA.
AC A0A3B4DYS9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Forkhead box protein A1-like {ECO:0000313|Ensembl:ENSPNAP00000028159.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000028159.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000028159.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_017578910.1; XM_017723421.1.
DR AlphaFoldDB; A0A3B4DYS9; -.
DR STRING; 42514.ENSPNAP00000028159; -.
DR Ensembl; ENSPNAT00000000722.1; ENSPNAP00000028159.1; ENSPNAG00000013736.1.
DR GeneID; 108443037; -.
DR CTD; 3171; -.
DR GeneTree; ENSGT00940000166203; -.
DR OMA; HDLPEWN; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0019904; F:protein domain specific binding; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR CDD; cd20040; FH_FOXA3; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR047366; FH_FOXA3.
DR InterPro; IPR013638; Fork-head_N.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR018533; Forkhead_box_C.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF201; HEPATOCYTE NUCLEAR FACTOR 3-GAMMA; 1.
DR Pfam; PF00250; Forkhead; 1.
DR Pfam; PF08430; Forkhead_N; 1.
DR Pfam; PF09354; HNF_C; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
FT DOMAIN 142..236
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 142..236
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 111..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 48327 MW; D3A83FF289967938 CRC64;
MLSSVKMECG EVGEWSLYSE PSEMYSSPSA TNSVSGLNSY INLNSAGSGS GMNMGYPGPG
LSTSPLTGMG GAINHMNLSP VGTSLNPNSL TQLSSPGSSL GPLSHYQSIS QPMSQLSYPS
PTSLTRPKEV PKPYRRSLTH AKPPYSYISL ITMAIQQSSN KMLTLNEIYQ WIMDLFPYYR
ENQQRWQNSI RHSLSFNDCF VKVARSPDKP GKGSYWTLHP NSGNMFENGC YLRRQKRFKI
EDKPGKKSTN SGKSQEGGNG KNGHQDGIHE DHSPAAGSDG ADSAQSDASH SGSASEEPQR
NLVPLDCPSQ ATSLAHSSPL PIPSSVPTSM PTSSSHLHSQ GMGAGAHLLP SPLSSPMHQH
LDLQNDHLKS MDPHYNFNHP FSITNLMSNE QKMDLKSYQD QVMAYNSYAA SSPVAAKQIY
DSAGPSAMDS GAYYQTLYSR SVLNAS
//
