ID A0A3B4DZG2_PYGNA Unreviewed; 568 AA.
AC A0A3B4DZG2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Cadherin 7 {ECO:0000313|Ensembl:ENSPNAP00000028451.1};
GN Name=CDH7 {ECO:0000313|Ensembl:ENSPNAP00000028451.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000028451.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000028451.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Cadherins are calcium-dependent cell adhesion proteins.
CC {ECO:0000256|RuleBase:RU004357}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251,
CC ECO:0000256|RuleBase:RU003318}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004251, ECO:0000256|RuleBase:RU003318}.
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DR AlphaFoldDB; A0A3B4DZG2; -.
DR Ensembl; ENSPNAT00000014740.1; ENSPNAP00000028451.1; ENSPNAG00000014305.1.
DR GeneTree; ENSGT00940000157031; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 3.
DR Gene3D; 2.60.40.60; Cadherins; 4.
DR Gene3D; 4.10.900.10; TCF3-CBD (Catenin binding domain); 1.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR000233; Cadherin_Y-type_LIR.
DR InterPro; IPR027397; Catenin-bd_sf.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR PANTHER; PTHR24027:SF91; CADHERIN-7; 1.
DR Pfam; PF01049; CADH_Y-type_LIR; 1.
DR Pfam; PF00028; Cadherin; 2.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 3.
DR SUPFAM; SSF49313; Cadherin-like; 3.
DR PROSITE; PS00232; CADHERIN_1; 1.
DR PROSITE; PS50268; CADHERIN_2; 3.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043};
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003318};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003318};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 38..126
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 127..230
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 231..378
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 568 AA; 62415 MW; CF0DE2F0BC4323A2 CRC64;
ADRQSRALAT ADRQSKALAT ADRQSKALAT ADRQSRALAT AERNQHHVDK GDGNVKYVLT
GEGASSIFTI DENTGDIHAT KRLDREEQGY YTLRAQAVDR ETNIPVEDES EFIVKVQDIN
DNEPKFPDGP YTAGVPEMSP LGTTVVQVAA TDADDPTYGH SARVVYSIIH GQPYFSVEPK
TALPNMDRET RDEYVLVIQA KDMMGQLGGL SGTTSVTVTL TDVNDNPPRF SRKLYQYSVL
ESVPVASVVA RLKAADPDIG SNAEMDYRIV DGDGPGLFNI TTDEETQEGV IILQRVRTHL
YYTFTTLELR NEAAHYSDFT LEYNTASVLT KRGGFRRREQ ALYQLPVLIV DSGSPALSST
NTLSVRVCDC DGDGVPQACG AVAYTLPAGL STGALLAILG CIFTLLGKTC PLILDDERDV
RENIVRYDDE GGGEEDTEAF DMVTLRNLNI MRDPKVRRDV TPETPTFFSY PSSSASRAAY
KVLPDNMLFR EFIWDRLKEA DVDPTAPPYD SLQTYAFEGT GSVAESLSSL ESLSSDSEQS
YDYLSNWGPR FKKLADLYGT MEGSGVFS
//
