ID   A0A3B4E039_PYGNA        Unreviewed;       776 AA.
AC   A0A3B4E039;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000028624.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000028624.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3B4E039; -.
DR   STRING; 42514.ENSPNAP00000028624; -.
DR   Ensembl; ENSPNAT00000014972.1; ENSPNAP00000028624.1; ENSPNAG00000014407.1.
DR   GeneTree; ENSGT01100000263565; -.
DR   OMA; DVMYNVY; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR   InterPro; IPR017979; GPCR_3_CS.
DR   InterPro; IPR004073; GPCR_3_vmron_rcpt_2.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR   PANTHER; PTHR24061:SF0; VOMERONASAL 2, RECEPTOR 23-RELATED; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00248; GPCRMGR.
DR   PRINTS; PR01535; VOMERONASL2R.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS00981; G_PROTEIN_RECEP_F3_3; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170}; Signal {ECO:0000256|SAM:SignalP};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           16..776
FT                   /note="G-protein coupled receptors family 3 profile domain-
FT                   containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017308832"
FT   DOMAIN          512..776
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   776 AA;  85696 MW;  DEDE25C5893AEA3B CRC64;
     CFYLLFNSVL FSVLSDVELR SYRWLQTMIF TVEEINRNPV LLPNLTLGYL ATDTCLSEGS
     TLSAALSIVT GQDKAVTEQC TKAPNVLTIT ILFLSLFPFF FCAPHLQVSY FASCACLSDR
     TRYPTFLRTV PSDAFQAQAM ARLLRQMGWS WVGVIYGDDA YGKSGVQLLI QELEGSGVCV
     DYTEVIPKSH ALEKIKRIVE RIQSSKAQVV VTFAISPDIE VLLKEVVRQN ATDRQWIATE
     AWSTSTHYSA WSGISLVGTL GFALRRVDIQ GLGSYLTQLS PEEHTNEQLV QNVWEEVFGC
     KFGKEMYSGP HCTGLEKVEV QGEAYFDVMY NVYKAVYAIA NAIQDMLDCR PGKGPFKNGE
     CPDINPVKPE QFTTPVGELV HFDNNGDPSA SYDIINWHMG AEGKVEFVKV GQFDAARGPQ
     QDFQLDLSKV NRLYIIQVPV SVCSESCPPG TRKAVQKGKP VCCYDCIPCA TGEISNANSR
     ECTKCLERFW SNTDRTECIP MLVEFLSFQD IMGIILSVLS IAGATLTGTV LTAFFYHRDT
     PLVRGNNSEL SFLLLLSLKL CFLCALAFIG RPAPWSCMLR HSLFGISFVV CLACVLSKTV
     VVLVAFRETL PGSNIMRYFG PAQQRAGIFV CTLVQVLICV LWLVLAPPLP TESAGGELGA
     RVVLLCAVGS VIGFSLVLGY IGLLAAICFL LAFFARKLPD NFNEAKFITF SMLIFCAVWI
     AFVPAYVSSP GKYTVAVEVF AILASSYGLL LCIFAPKCYI ILLKPEKNTK KSMMAK
//