ID   A0A3B4E5K9_PYGNA        Unreviewed;       966 AA.
AC   A0A3B4E5K9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Disheveled-associated activator of morphogenesis 1-like {ECO:0000313|Ensembl:ENSPNAP00000031055.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000031055.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000031055.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4E5K9; -.
DR   Ensembl; ENSPNAT00000019686.1; ENSPNAP00000031055.1; ENSPNAG00000018221.1.
DR   GeneTree; ENSGT00940000156452; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   Gene3D; 1.10.238.150; Formin, FH3 diaphanous domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR014767; DAD_dom.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   InterPro; IPR010472; FH3_dom.
DR   InterPro; IPR014768; GBD/FH3_dom.
DR   InterPro; IPR010473; GTPase-bd.
DR   PANTHER; PTHR45725:SF16; DISHEVELED-ASSOCIATED ACTIVATOR OF MORPHOGENESIS 1; 1.
DR   PANTHER; PTHR45725; FORMIN HOMOLOGY 2 FAMILY MEMBER; 1.
DR   Pfam; PF06367; Drf_FH3; 1.
DR   Pfam; PF06371; Drf_GBD; 1.
DR   Pfam; PF02181; FH2; 1.
DR   SMART; SM01139; Drf_FH3; 1.
DR   SMART; SM01140; Drf_GBD; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51231; DAD; 1.
DR   PROSITE; PS51444; FH2; 1.
DR   PROSITE; PS51232; GBD_FH3; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          45..420
FT                   /note="GBD/FH3"
FT                   /evidence="ECO:0000259|PROSITE:PS51232"
FT   DOMAIN          500..896
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   DOMAIN          914..946
FT                   /note="DAD"
FT                   /evidence="ECO:0000259|PROSITE:PS51231"
FT   REGION          875..922
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          936..966
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          438..507
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        875..916
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        936..953
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   966 AA;  112483 MW;  BE75E0DE1D37CF58 CRC64;
     MAPRKRGGGG RSMSFIFCCF QSSDHPEITY RLREDFVLQT MEPTLPIPSY DELDAMFSEL
     VDELDLTEKH REAMFALPAE KKWQIYCSKK KEQEENKGAT SWPEYYIDQL NSMAARKTLL
     ALEKEEEEER NKTIESLKTA LRTQPMRFVT RFIDLDGLTC ILNFLKSMDY ETTESQIHTS
     LIGCIKALMN NSQGRAHVLS HPESINIIAQ SLATENIKTK VAVLEIMGAV CLVPGGHKKV
     LEAMLHYQKF ACERTRFQML LNDLDRSTGR YRDEVSLKTA IMSFINAVLS QGAGETSLEF
     RVHLRYEFLM LGIQPIIDKL RSHENSTLDR HLDYFEMLRN DDELTVSRRF ESVHVDTKSA
     SQVFDLIRKK MTHTDAYPHF MSILHHCLLM PHKRSGNTVQ YWLLLDRIVQ QMVLQNDKGH
     DPDVTPLENF NVKNVVRMLV NENEVKQWKE QAEKMRKDHH ELQQKMEKKE RECDAKTQEK
     EEMMQTLNKM KEKLEKETTE HRLVKQQVSE LGVRLHELST NKLEGTVWAE VDDGKVFKIL
     DLADIEKTFS AYQRQQKEAE DDTLSSKKVK ELSVIDGRRA QNCNILLSRL KLSNEEMKRA
     ILTMDEQEDL PKDMLEQMLK FVPEKSDVDL LEEHKHELDR MAKADRFLYE MSRINHYQQR
     LQSLYFKKKF AERIAEIKPK VEALTKASKE MLQSRNLKQL LEVVLAFGNY MNKGQRGNAF
     GFKVSSLNKI ADTKSSIDKN ITLLHYLITI LEKKYPKVMQ IPEDLQNVPE AAKVNMTELE
     KEINNLRSGL KSVESELEFQ KKCPQEVGDK FVSVVSQFVT LASFSFSDVE DSLSEAKELF
     LKAVKHFGED ATKMQPDEFF GIFDQFLQSF AEARQENENM RRRKEEEERR ARMEAQLKEQ
     REKERKARKA KENGEDDGGE FDDLVSALRS GEVFDKDLSK MKRNRKRINS QTTDTGRERP
     ITKLNF
//