ID   A0A3B4ECE4_PYGNA        Unreviewed;       152 AA.
AC   A0A3B4ECE4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=ProAM N-terminal 20 peptide {ECO:0008006|Google:ProtNLM};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000033505.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000033505.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the adrenomedullin family.
CC       {ECO:0000256|ARBA:ARBA00010575}.
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DR   AlphaFoldDB; A0A3B4ECE4; -.
DR   STRING; 42514.ENSPNAP00000033505; -.
DR   Ensembl; ENSPNAT00000024392.1; ENSPNAP00000033505.1; ENSPNAG00000022122.1.
DR   GeneTree; ENSGT01090000260230; -.
DR   OMA; KGCQFGT; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR   InterPro; IPR021116; Calcitonin/adrenomedullin.
DR   PANTHER; PTHR23414; ADRENOMEDULLIN, ADM; 1.
DR   PANTHER; PTHR23414:SF3; PRO-ADRENOMEDULLIN; 1.
DR   Pfam; PF00214; Calc_CGRP_IAPP; 1.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          133..152
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   152 AA;  16663 MW;  61EB373A84FCD699 CRC64;
     MVSSQSSSRS SPSSPANLGS RRRGHCMMTV AVLLFLYMPV TTAVAVRHSL RPQTDPLSLI
     NSLQTAEEFV TSVDRHKGTP STATNSRTTE VPTPLRNILI KSIRARSRRA VQRGCQFGTC
     QVHNLANTLY MMGQKTGKEQ SKKATDPNGY GR
//