ID A0A3B4EEB7_PYGNA Unreviewed; 623 AA.
AC A0A3B4EEB7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=XK-related protein {ECO:0000256|RuleBase:RU910716};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000033571.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000033571.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phospho-L-serine(in) = a 1,2-diacyl-
CC sn-glycero-3-phospho-L-serine(out); Xref=Rhea:RHEA:38663,
CC ChEBI:CHEBI:57262; Evidence={ECO:0000256|ARBA:ARBA00024479};
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU910716}.
CC -!- SIMILARITY: Belongs to the XK family. {ECO:0000256|ARBA:ARBA00008789,
CC ECO:0000256|RuleBase:RU910716}.
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DR RefSeq; XP_017561475.1; XM_017705986.1.
DR AlphaFoldDB; A0A3B4EEB7; -.
DR Ensembl; ENSPNAT00000024580.1; ENSPNAP00000033571.1; ENSPNAG00000022298.1.
DR GeneID; 108432262; -.
DR CTD; 114786; -.
DR GeneTree; ENSGT01070000253766; -.
DR OMA; LWDGLWI; -.
DR OrthoDB; 3385375at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR018629; XK-rel.
DR PANTHER; PTHR16024; XK-RELATED PROTEIN; 1.
DR PANTHER; PTHR16024:SF16; XK-RELATED PROTEIN 4; 1.
DR Pfam; PF09815; XK-related; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910716};
KW Transmembrane {ECO:0000256|RuleBase:RU910716};
KW Transmembrane helix {ECO:0000256|RuleBase:RU910716}.
FT TRANSMEM 76..93
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 113..137
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 220..241
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 303..321
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 341..362
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 369..388
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 400..416
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 428..447
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 459..482
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT REGION 19..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 623 AA; 69928 MW; D8020435CAEF7EC5 CRC64;
MAAKSDGVLK MKKSDVAFTP LQNSDHSGSV QGLAPGSQPD SGAGEADFNV NGGSRCCGGG
GSNSTCLRLG RERQRYTVWD CLWILAAVAV YFADVGTDVW LSVDYYLRRD YWWFGLTLFF
VVLGSFSVQV FSFRWFVHDF GAADGSSSSS GCSHMDGKLL SCSASHGDVG AAHPSTPQRQ
ASTASKSNTN TTATNSSSNS SSSTTNAART NQKRSASCSF CIWLMQSVIH ILQLGQIWRY
FHTIYLGIRS RRSGENDRWR FYWRMVYEYA DVSMLHLLAT FLESAPQLVL QLCIIIQTHK
LQAVQGMTAA ASLVSLAWAL ASYQKALRDS RDDKKPLSYL AVIIQFCWHF FTIAARVVTF
ALFASVFQLY FGIFIVLHWC VMTFWIVHCE TEFCITKWEE IVFDMVVGII YIFSWFNVKE
GRTRCRLFVY YLVILLENAA LSTLWYLYRI PASTDAFAVP ALCVIFSSFL TGVVFMLMYY
AFFHPNGPRF GRSSSLTQLD EASAAFAMPS EGATNSLRSN RGGTLARDAD REAKYGTERD
GCVPVFQVRP TAPSTPSSRA PRLEETVIRI DLCRNRYPAW ERHVLDRSIR KAILAIDSSP
TPPRLQYKDD TLVQERLEYE TTL
//
