ID   A0A3B4EGV9_PYGNA        Unreviewed;       619 AA.
AC   A0A3B4EGV9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=Transporter {ECO:0000256|RuleBase:RU003732};
GN   Name=SLC6A13 {ECO:0000313|Ensembl:ENSPNAP00000035090.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000035090.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000035090.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the sodium:neurotransmitter symporter (SNF) (TC
CC       2.A.22) family. {ECO:0000256|RuleBase:RU003732}.
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DR   RefSeq; XP_017556664.1; XM_017701175.1.
DR   AlphaFoldDB; A0A3B4EGV9; -.
DR   STRING; 42514.ENSPNAP00000035090; -.
DR   Ensembl; ENSPNAT00000027605.1; ENSPNAP00000035090.1; ENSPNAG00000024834.1.
DR   GeneID; 108429445; -.
DR   CTD; 6540; -.
DR   GeneTree; ENSGT00940000157478; -.
DR   OMA; FTPAVCM; -.
DR   OrthoDB; 3084493at2759; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   CDD; cd11496; SLC6sbd-TauT-like; 1.
DR   InterPro; IPR000175; Na/ntran_symport.
DR   InterPro; IPR037272; SNS_sf.
DR   PANTHER; PTHR11616:SF118; SODIUM- AND CHLORIDE-DEPENDENT BETAINE TRANSPORTER; 1.
DR   PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR   Pfam; PF00209; SNF; 1.
DR   PRINTS; PR00176; NANEUSMPORT.
DR   SUPFAM; SSF161070; SNF-like; 1.
DR   PROSITE; PS00610; NA_NEUROTRAN_SYMP_1; 1.
DR   PROSITE; PS00754; NA_NEUROTRAN_SYMP_2; 1.
DR   PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Symport {ECO:0000256|RuleBase:RU003732};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU003732};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003732}.
FT   TRANSMEM        41..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        72..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        115..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        207..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        238..261
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        281..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        318..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        376..409
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        421..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        451..476
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        497..519
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        531..554
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          592..619
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   619 AA;  70267 MW;  C82C1666ABB0B2B0 CRC64;
     MTGEKDIRCK MDPSNGLNRS LDIVPTTEEK MKDRGQWSNK LEFVLSVAGE IIGLGNVWRF
     PYLCYKNGGG AFFIPYLIFL ATCGIPVFFL ETALGQYTSE GGITCWRKIS PLFEGVGYAT
     QVIVALLNVY YIIVLAWGIF YLAFSFSSSL PWSSCNNTWN TDSCMEFQRR NKSFDQNHME
     NATSPVIEFW ERRVLRISSG IDEIGELHWD MALCLLLAWI LCYFCIWKGV KSTGKVVYFT
     ATFPYVMLII LLIRGITLPG ASRGIQFYLY PDLGRLADPQ VWMDAGTQIF FSYAICLGCL
     TALGSYNKYN NNCYKDCLAL CFLNSGTSFV AGFAIFSILG FMSFEQNVPI SEVAESGPGL
     AFIAYPRAVS MMPFSPLWAC FFFIMIVLLG LDSQFVCVES LVTAIVDMYP STFRRKNRRE
     LLILAVAIVS FLFGLIMLTE GGMYVFQLFD YYAASGMCLL FVAIFETVCI AWIYGADRFY
     DNIEDMIGYR PGPYIKYCWL FLTPATCFGT FAFSLIKYTP LKYNNEYVYP WWGYALGWLL
     ALSSMVCIPL WIIYKMGTAK GTLRERFHEL STPSPDLPKT RREQEKLQAI FSADGDSLRQ
     RGAPTKDGYF PVNEKESHC
//