ID A0A3B4EII0_PYGNA Unreviewed; 527 AA.
AC A0A3B4EII0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=ETS transcription factor ELK1 {ECO:0000313|Ensembl:ENSPNAP00000035006.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000035006.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000035006.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC ECO:0000256|RuleBase:RU004019}.
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DR RefSeq; XP_017575924.1; XM_017720435.1.
DR AlphaFoldDB; A0A3B4EII0; -.
DR STRING; 42514.ENSPNAP00000035006; -.
DR Ensembl; ENSPNAT00000027467.1; ENSPNAP00000035006.1; ENSPNAG00000024652.1.
DR GeneID; 108441100; -.
DR CTD; 2002; -.
DR GeneTree; ENSGT00940000157571; -.
DR OMA; LPSRYPW; -.
DR OrthoDB; 2884081at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849; ETS; 1.
DR PANTHER; PTHR11849:SF178; ETS DOMAIN-CONTAINING PROTEIN ELK-1; 1.
DR Pfam; PF00178; Ets; 1.
DR PRINTS; PR00454; ETSDOMAIN.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW Nucleus {ECO:0000256|RuleBase:RU004019}.
FT DOMAIN 14..94
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS50061"
FT REGION 178..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 243..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 348..426
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..373
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..408
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 527 AA; 55937 MW; 09ED79BEFFEA1EA9 CRC64;
MDSNPLISAM DPSITLWQFL LHLLDDQSHR HLISWTSGDG EFKLLDAEEV ARLWGLRKNK
TNMNYDKLSR ALRYYYDKNI IKKVSGQKFV YKFVTFPDPN SADGLRGPED GQRVGVGEKV
EVSIQPKSAV GAGATTGCLS KNLQTQRSSP SSVQRSSRND YMKSGLYSTF TIQSLQTPCK
SSPKPIKTEL PVDNTPKPAS LDRPVHEVRV CQPEGQPSAM QSPPTVDNSS LQVIVTHPSP
CATPALSPQT PSGSTAATTN VQTQKSQGLG DPPQIYLTSV SDPGSLTPLI PLTPVAAGDC
VVNPSQGHPV FVVIKPSPVG GAKESTLSAG EDLLEIVDLD VKPEAETLST SAPVAVEAPG
PVDAPPPCPE PMAQPVVEGE LKDEPEQPED TNTPPASHPV STQEVQPPKS KKPRVLELPS
SPSQLAPGFS LDKVNAAVNS LLAPGSATNT LTPTVITSHA LTPVLLTPSP LPSTIHFWST
LSPIAPRSPA KLSFQFPTNG SNQINIPALS VDGLSTPVVL SPGPQKP
//
