ID A0A3B4EK26_PYGNA Unreviewed; 379 AA.
AC A0A3B4EK26;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Cysteine and histidine rich 1 {ECO:0000313|Ensembl:ENSPNAP00000036245.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000036245.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000036245.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ZFTRAF1 family.
CC {ECO:0000256|ARBA:ARBA00034319}.
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DR RefSeq; XP_017551369.1; XM_017695880.1.
DR AlphaFoldDB; A0A3B4EK26; -.
DR STRING; 42514.ENSPNAP00000036245; -.
DR Ensembl; ENSPNAT00000030431.1; ENSPNAP00000036245.1; ENSPNAG00000005034.1.
DR GeneID; 108426421; -.
DR CTD; 50626; -.
DR GeneTree; ENSGT00390000018258; -.
DR OMA; RTDEFIH; -.
DR OrthoDB; 5491349at2759; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd22861; CYHR1_C; 1.
DR CDD; cd16505; RING-HC_CYHR1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR039338; ZFTRAF1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR23059; CYSTEINE AND HISTIDINE-RICH PROTEIN 1; 1.
DR PANTHER; PTHR23059:SF4; CYSTEINE AND HISTIDINE-RICH PROTEIN 1; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
DR PROSITE; PS50145; ZF_TRAF; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 86..131
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 152..190
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT ZN_FING 152..190
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 379 AA; 42301 MW; 8246EF6B8D777B08 CRC64;
MEERGELAVA AAPGSSSSGL GVGPVGGALE AGQASSGLAG IQEEPGGRRD ASGPETDADA
PPKKRVRLQE GEAGKLEERL YSVLCCTVCL DLPKASVYQC TNGHLMCAGC FIHLLADARL
KEEQATCPNC RCEISKSLCC RNLAVEKAVS ELPSDCSYCL KQFPRSSLDH HQTEECQDRL
TQCKYKRIGC PWQGPYHELS AHEVECCHPS KTGIELMGIL EEMDQSHRRE LQLYNSIFSL
LSFEKIGFTE VQFRPYRTDD FITRLYYETP RFTVLNQTWV LKARVNDSER NPNLSCKRTL
SFQLILKSKV NSALECSFLL LKGPYDDVKI KPVIQHHVFS NDANETEYAP LPISDSVECN
KLLAAKNINL RLFIFQIQK
//
