ID A0A3B4ELZ4_PYGNA Unreviewed; 369 AA.
AC A0A3B4ELZ4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Bone morphogenetic protein 2-like {ECO:0000313|Ensembl:ENSPNAP00000036798.1};
OS Pygocentrus nattereri (Red-bellied piranha).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Pygocentrus.
OX NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000036798.1, ECO:0000313|Proteomes:UP000261440};
RN [1] {ECO:0000313|Ensembl:ENSPNAP00000036798.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR AlphaFoldDB; A0A3B4ELZ4; -.
DR Ensembl; ENSPNAT00000031872.1; ENSPNAP00000036798.1; ENSPNAG00000027948.1.
DR GeneTree; ENSGT00940000165063; -.
DR Proteomes; UP000261440; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13765; TGF_beta_ADMP; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF241; ANTI-DORSALIZING MORPHOGENETIC PROTEIN; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 249..369
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 369 AA; 41748 MW; 5C63957507D7C5A0 CRC64;
MFGKLHLRKP LSSQVHFKTA DTTQLSKGES EEVRSAALKR LLEVFGLEDH PASPPRSHKQ
PPQYMLDLYN TVADVDGVTK DPTVLEGNTV RSFFDKLRSD EIEFLFNLST VARSETVLTA
ELHLFKLRPQ ASLTFNRHHF CQVSVYQVTD SSKMNISQSK KLVSSRLIPI HSNGWEVFTI
TQAIRTWTLD EHSNLGLLVT VKALSGSRID LRTVRFASGG SHHHSKQPML VLFTDDGRRA
PSMEVALRGH RRARSIDYEE DRDKMPCQRL PLYVDFEEIG WSGWIVSPRG YNAYHCKGSC
PFPLGQNMRP TNHATVQSII NALKLTKGIE MPCCVPDKLF SINLLYFDDD ENVVLKQYDD
MVAGSCGCH
//
