ID   A0A3B4EPE8_PYGNA        Unreviewed;       438 AA.
AC   A0A3B4EPE8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=E3 ubiquitin/ISG15 ligase TRIM25-like {ECO:0000313|Ensembl:ENSPNAP00000037144.1};
OS   Pygocentrus nattereri (Red-bellied piranha).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Pygocentrus.
OX   NCBI_TaxID=42514 {ECO:0000313|Ensembl:ENSPNAP00000037144.1, ECO:0000313|Proteomes:UP000261440};
RN   [1] {ECO:0000313|Ensembl:ENSPNAP00000037144.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_017578467.1; XM_017722978.1.
DR   AlphaFoldDB; A0A3B4EPE8; -.
DR   STRING; 42514.ENSPNAP00000037144; -.
DR   Ensembl; ENSPNAT00000032768.1; ENSPNAP00000037144.1; ENSPNAG00000028520.1.
DR   GeneID; 108442782; -.
DR   GeneTree; ENSGT00940000163587; -.
DR   OMA; YCMDDKM; -.
DR   OrthoDB; 2939962at2759; -.
DR   Proteomes; UP000261440; Unplaced.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd19802; Bbox1_TRIM8-like; 1.
DR   Gene3D; 4.10.830.40; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR027370; Znf-RING_euk.
DR   InterPro; IPR000315; Znf_B-box.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR25465:SF36; E3 UBIQUITIN-PROTEIN LIGASE TRIML1-RELATED; 1.
DR   Pfam; PF00643; zf-B_box; 1.
DR   Pfam; PF13445; zf-RING_UBOX; 1.
DR   SMART; SM00336; BBOX; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50119; ZF_BBOX; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00024}.
FT   DOMAIN          17..59
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          159..200
FT                   /note="B box-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50119"
FT   REGION          374..438
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          208..235
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        379..438
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   438 AA;  50581 MW;  6A095B4625501A7C CRC64;
     MATAVEDTSV LEEELTCPVC LDLYRDPRLL PCGHNFCLPC LRKLKGRSER GRLRCPECRQ
     SHRCTVPWQK NFKLANIADG FRRRSQAERP VSGRQSPTCR TEGVRCDYCP IAPMDMSKGS
     TAVKTCLKCE VSMCPEHVQP HLELPAFREH PLVEPLGDLR KRKCAEHDEM FRYYCVDECT
     FLCNACTIEG GHSGHSIKTL KNTMKDMRAS LDMDLQKADR KIRKVERNVQ DQTEVEHQNK
     AFMEEAEQRV EALRGTLSTR LEGFLSSLCE SLHMHEAENS LSVQQNLTCI AEDRSRLADV
     HTGIERLLQE HDPFQFIKEY SSCAKRYRRL LRRPLFLAHS MPIDMDSLGA IMEGRMEEFM
     TDMRQQIISL IDTLCAGDDR DEGVEEDESE ESDENEDDGS EEDGEEEEEM RSEEEQDHSE
     YTDEDYTPEE EEEEEEDQ
//