ID   A0A3B4ESV1_9CICH        Unreviewed;       808 AA.
AC   A0A3B4ESV1;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   SubName: Full=Catenin alpha 1 {ECO:0000313|Ensembl:ENSPNYP00000000241.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000000241.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000000241.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the vinculin/alpha-catenin family.
CC       {ECO:0000256|ARBA:ARBA00008376}.
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DR   AlphaFoldDB; A0A3B4ESV1; -.
DR   Ensembl; ENSPNYT00000000248.1; ENSPNYP00000000241.1; ENSPNYG00000000187.1.
DR   GeneTree; ENSGT01030000234543; -.
DR   Proteomes; UP000261460; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 6.10.250.2510; -; 1.
DR   Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 4.
DR   InterPro; IPR036723; Alpha-catenin/vinculin-like_sf.
DR   InterPro; IPR006077; Vinculin/catenin.
DR   PANTHER; PTHR18914; ALPHA CATENIN; 1.
DR   PANTHER; PTHR18914:SF24; CATENIN ALPHA-1; 1.
DR   Pfam; PF01044; Vinculin; 2.
DR   PRINTS; PR00806; VINCULIN.
DR   SUPFAM; SSF47220; alpha-catenin/vinculin-like; 4.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   REGION          764..796
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        765..785
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   808 AA;  90003 MW;  AFAE013D8A4AB941 CRC64;
     MTSNTAPNIN FKWDPKSLEI RTLAVERLLE PLVTQVTTLV NTSNKGPSNK RKGRSKKAHV
     LAASVETATE NFLEKGEKIA KESQFLKDEL TAAVEDVRKQ GILKIRIAAV WLHACTEFVV
     VVQGVQRQKK KDNMALSLLV FHLTSESVSS VISFLVTLGF VKERSVYHDD CAFFAPCVIF
     PLTLSLQKQI IVDPLAFSEE RFRPSLEERL ESIISGAALM ADSSCTRDDR RERIVAECNS
     VRQALQDLLS EYMGNAGRKD RSDALNTAID RMTKKTRDLR RQLRKAVMDH VSDSFLETNV
     PLLVLIEAAK NGNEKEVKEY AQVFREHANK LIEVANLACS ISNNEEGVKL VRMAASQLES
     LCPQVINAAL ALAAKPNSKV AQDNMDLFKE QWEKQVRVLT DAVDDITSID DFLCVSENHI
     LEDVNKCVIA LQEKDVDGLD RTAGAIRGRA ARVVHVVTSE MDNYEPGVYT EKVLEATKLL
     TDTVMPRFTE QVESAVEALS ANPSQPVDEN EFIDASRLVY DGIRDIRKAV LMIRTPEELD
     DSDFETEDFD VRSRTSVQTE DDQLIAGQSA RAIMAQLPQE QKAKIAEQVA SFQEEKSKLD
     AEVSKWDDSG NDIIVLAKQM CMIMMEMTDF TRGKGPLKNT SDVISAAKKI AEAGSRMDKL
     GRTIADHCPD SSCKQDLHAY LQRIALYCHQ LNICSKVKAE VQNLGGELVV SGLDSAMSLI
     QAAKNLMNAV VSTVKASYVA STKYQKNKGM EALNMPAVSW KMKAPEKKPL VKREKQDDGQ
     TNRVKRSSQR KHVNPVQALS EFKAMDSI
//