ID A0A3B4ESW4_9CICH Unreviewed; 1452 AA.
AC A0A3B4ESW4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=ATPase family AAA domain containing 2B {ECO:0000313|Ensembl:ENSPNYP00000000843.1};
DE SubName: Full=ATPase family AAA domain-containing protein 2B {ECO:0000313|RefSeq:XP_005725126.1};
GN Name=ATAD2B {ECO:0000313|Ensembl:ENSPNYP00000000843.1};
GN Synonyms=atad2b {ECO:0000313|RefSeq:XP_005725126.1};
OS Pundamilia nyererei.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000000843.1, ECO:0000313|Proteomes:UP000261460};
RN [1] {ECO:0000313|Ensembl:ENSPNYP00000000843.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_005725126.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005725126.1; XM_005725069.1.
DR STRING; 303518.ENSPNYP00000000843; -.
DR Ensembl; ENSPNYT00000000861.1; ENSPNYP00000000843.1; ENSPNYG00000000706.1.
DR GeneID; 102208470; -.
DR CTD; 54454; -.
DR GeneTree; ENSGT00550000074694; -.
DR OrthoDB; 2783776at2759; -.
DR Proteomes; UP000261460; Unplaced.
DR Proteomes; UP000695023; Unplaced.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd05528; Bromo_AAA; 1.
DR CDD; cd19517; RecA-like_Yta7-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR045199; ATAD2-like.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR23069; AAA DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR23069:SF5; ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2B; 1.
DR Pfam; PF00004; AAA; 2.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00674; AAA; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Reference proteome {ECO:0000313|Proteomes:UP000695023}.
FT DOMAIN 957..1020
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1068..1274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1288..1387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..253
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1112..1132
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1158..1172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1201..1230
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1234..1250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1288..1317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1318..1335
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1452 AA; 163133 MW; 824FF23D435A02BC CRC64;
MVNTRKSSRT RSGPFISSRT RSSSRNERNS EEHKEPSSDA SSPSSPRFAP PSKRTRRQTA
SEPSSSDTSP SPQTKGQRVS WGIPTYCTRL SSRIMQNGHA HMSHRNEESG GGDHSHMNGH
VELKRSCRVK KSQFEHLNQS LLFDQLVNST AEAVLQEMDN ISSIRQNREV ERLRMWTGET
EEENMDMYSR VKRRKSMRRS TFNIPAHHKV MGKTEQEEEE EEGTEESHGE EEEEDAEDDD
DDDEGDEAEE AGEENDRPYN LRQRKTVQRY EAPPIEPVNR KQSNPSLFDT HRSPARRSHI
RVKKHAIHSS DTTSSSDEER FERRKSKSMT RARNRCLPMN LTAEDLASGV LRDRVKVGAS
LADVDPMNLD PSVRFDNVGG LSNHIQSLKE MVVFPLLYPE IFEKFKIQPP RGCLFYGPPG
TGKTLVARAL ANECSHGDRK VSFFMRKGAD CLSKWVGESE RQLRLLFDQA YLMRPSIIFF
DEIDGLAPVR SSKQDQIHSS IVSTLLALMD GLDSRGEIVV IGATNRLDSI DPALRRPGRF
DREFLFSLPD KKARKHILEI HTRDWNPKLS EPFLDELAEK CVGYCGADIK ALCTEAALMA
LRRRYPQIYG SSVKLKLDVA SIVLGPGDFS KAMRTIVPAS QRALAPPGRA LSPTLRPLLA
TSFSLVLKAL LRVFPHAQCT DRDNTHVLGG DNHLLEEDLY SDDDNEEGSA SIYEVQPAAS
PKSQLTSSAM HRPFLHFSSS ALQQPTAYRP RLLLAGAPGS GQSSHLAPAL LHHLDKLPVH
RLDLPTLYSV SAKTPEESCA QVFREARRSV PSVVYMPHIS EWWDTVSDTV KSTFLTLLQD
VPSFSPVLVL ATAETHYSKL SDEVRSIFQR TYGEVVALSP PGEEEIRHFF SDLLLVQAAR
PPPRLRNADK CEEVLPVAEA PGPRVLSAEE QRRLAEQEEN TLRELRLFLR DVTKRLATDK
RFNIFSKPVD IEEVSDYLEV IRQPMDLSTV MTKIDTHQYL TAKDFLVDID LICSNALEYN
PDKDPGDKVI RHRACSLKDT AHAIFAAELD PEFDRMCEEI KEARRKRDLL TPAQLSAVPG
AGATRKHHSA GEEQPRSSTQ GDATEKHCTT NYVKRKVRRR PSWGRGIIRK KKNYKKGTEE
EEEEPEAEVE AAGPSDSCLT QDEESSCDIT GPQPNGHHPH APSTEEESSN EPPVAAPDKP
PDASEAREAP MPKVEEPAAK EAEPEITGKH TEPHCLGGSS QPNTDGDSEA SRADFQPLIE
MSVSSDAEDQ PKHTEVLLVS QVDCVNGNES MDSLDLQSLK GSSEAETRTP QSTAEGSNRA
EQDEHKDKNE SKPTQEQHPQ DGVAVTETVE EDHNKEVGTF NSSSSEQLKE SAERTEEEPQ
AVPPHPPVVI DHQRLLILLD MVVKKSEGYS VEQLERLYSL LSQCIYKHRR EYDKTQLLEE
MEERIQRFDT FL
//
