ID   A0A3B4EUV9_9CICH        Unreviewed;       546 AA.
AC   A0A3B4EUV9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Integrin beta {ECO:0000256|RuleBase:RU000633};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000001099.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000001099.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU000633};
CC       Single-pass type I membrane protein {ECO:0000256|RuleBase:RU000633}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane
CC       protein {ECO:0000256|ARBA:ARBA00004479}.
CC   -!- SIMILARITY: Belongs to the integrin beta chain family.
CC       {ECO:0000256|ARBA:ARBA00007449, ECO:0000256|RuleBase:RU000633}.
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DR   AlphaFoldDB; A0A3B4EUV9; -.
DR   Ensembl; ENSPNYT00000001119.1; ENSPNYP00000001099.1; ENSPNYG00000000742.1.
DR   GeneTree; ENSGT01090000259987; -.
DR   Proteomes; UP000261460; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   Gene3D; 2.10.25.10; Laminin; 3.
DR   Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 2.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR   InterPro; IPR040622; I-EGF_1.
DR   InterPro; IPR015812; Integrin_bsu.
DR   InterPro; IPR002369; Integrin_bsu_VWA.
DR   InterPro; IPR032695; Integrin_dom_sf.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR10082; INTEGRIN BETA SUBUNIT; 1.
DR   PANTHER; PTHR10082:SF28; INTEGRIN BETA-1; 1.
DR   Pfam; PF18372; I-EGF_1; 1.
DR   Pfam; PF00362; Integrin_beta; 2.
DR   PRINTS; PR01186; INTEGRINB.
DR   SMART; SM00187; INB; 1.
DR   SUPFAM; SSF69179; Integrin domains; 1.
DR   SUPFAM; SSF103575; Plexin repeat; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
PE   3: Inferred from homology;
KW   Cell adhesion {ECO:0000256|RuleBase:RU000633};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU000633};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000633};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          32..371
FT                   /note="Integrin beta subunit VWA"
FT                   /evidence="ECO:0000259|SMART:SM00187"
SQ   SEQUENCE   546 AA;  61720 MW;  BD618F13B3C2792D CRC64;
     VHSHDGILEP LASFCSLADH SHHKCESQGV RSCGECLAAG PHCHIWERCD TAGALLKRGC
     PFDHLEDPRG STVLLKNRKI TFHPKEQRHK RLHRVVTQLQ PQTVLLHLRP GEPQSFEVKF
     KQVKDYLIDL YYLMDLSFSM EDDLMNVKKL GADLMKEMKN ITSDFRLCLF ASDMLRNPWG
     QRISSNLDSP EVGLNDLMQA TMCERQIGWR NVTRLLVFST DAVFHVAGDG KLSCIVLPND
     GKCHLLQLFT FFRRTIIFFF TKEKKFKLKW CFHYRSIIVG LALKWRLTAL LAIVSTGLAH
     LLYSHCKDHR PRHGEQGRRC SNISVDDEVS FNVSITAPLC VAASQRPCRF IIKPQGYSEE
     VEVLLSPICE CSCQKDRVPH SPSCSHGNRT LECGACRCKA GRAGTFSECE QEESGTAVDS
     HLCRRDNASE VCSGHRKCIC GRCVCQKSSK KPSHVYYGEL CECSDFSCDQ YRGLQCGRRG
     RCVWGECLCF PAFRGRAYEC LSQDGQICGG SHCGTCICHD KRFQGPTCEL CPSCPSICNL
     HHYYDL
//