ID   A0A3B4EZV3_9CICH        Unreviewed;       582 AA.
AC   A0A3B4EZV3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Dynein heavy chain 12, axonemal-like {ECO:0000313|Ensembl:ENSPNYP00000003750.1, ECO:0000313|RefSeq:XP_005740520.1};
GN   Name=ASB14 {ECO:0000313|Ensembl:ENSPNYP00000003750.1};
GN   Synonyms=LOC102205832 {ECO:0000313|RefSeq:XP_005740520.1,
GN   ECO:0000313|RefSeq:XP_013768217.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000003750.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000003750.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_005740520.1, ECO:0000313|RefSeq:XP_013768217.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
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DR   RefSeq; XP_005740520.1; XM_005740463.1.
DR   RefSeq; XP_013768217.1; XM_013912763.1.
DR   AlphaFoldDB; A0A3B4EZV3; -.
DR   STRING; 303518.ENSPNYP00000003750; -.
DR   Ensembl; ENSPNYT00000003846.1; ENSPNYP00000003750.1; ENSPNYG00000002934.1.
DR   GeneID; 102205832; -.
DR   CTD; 100535284; -.
DR   GeneTree; ENSGT00940000156550; -.
DR   OrthoDB; 5479200at2759; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000261460; Unplaced.
DR   Proteomes; UP000695023; Unplaced.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR   Gene3D; 1.10.750.20; SOCS box; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR001496; SOCS_box.
DR   InterPro; IPR036036; SOCS_box-like_dom_sf.
DR   PANTHER; PTHR24178:SF44; ANKYRIN REPEAT AND SOCS BOX PROTEIN 3; 1.
DR   PANTHER; PTHR24178; MOLTING PROTEIN MLT-4; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 3.
DR   Pfam; PF07525; SOCS_box; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 11.
DR   SMART; SM00253; SOCS; 1.
DR   SMART; SM00969; SOCS_box; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF158235; SOCS box-like; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 6.
DR   PROSITE; PS50088; ANK_REPEAT; 6.
DR   PROSITE; PS50225; SOCS; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Reference proteome {ECO:0000313|Proteomes:UP000695023}.
FT   REPEAT          116..148
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          182..214
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          215..247
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          247..279
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          312..344
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          384..416
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   DOMAIN          524..572
FT                   /note="SOCS box"
FT                   /evidence="ECO:0000259|PROSITE:PS50225"
SQ   SEQUENCE   582 AA;  65776 MW;  7A8EC0069602DA21 CRC64;
     MSMETEDDFY QSEEDLDEDE ATQYIIEQSL IQYRKLKGLN PSDLKPCEDP DEIFKAIKEG
     DENALNRLAA QPETLSRVDT RGWIPLHEAA AQQNKKVLEI IFSASPPGAA QCRTLKGETP
     LFLAVVHGLR ENATFLLQNG SNPDLQNDEQ DSPLVAALLN DQYDLATLLL RYNAKIDQTG
     PLDRTALHES AFLGLENFVY LLLESGANPN ACDVKKKTPL ALAAQNGHLN VVEVLLQKGA
     QVWCESESGT ILFDAAASGN PDIISLLLEH GADPNVTLYS GHLPIHRVAY HGHRLALEHL
     IPVTKLHAVK ESGMSPLHSA AAGGHAQCVE ILLKAGYDPN FMLHPRIRRN YDDDRKSALF
     FAVSNNDLQC TRLLLEAGAL VNQDPINCLQ VALRQGNYEL INILLKYGAN VNYYSRVNTT
     HFPSALQYAL KDEVMLRMIL NHGYDVKRCF DCPYGDSSHD YTAWTTSVIK DMVFCEVITV
     SWLKHLSAQV VRIMLDYTDH VSFCTKLKDT LQEQKQWPEI CHIQRNVRSL KHLCRLRIRE
     HLRRLRLRAP AFINFLPLPP RLKDYLRYKE FDIYSRGSMI IP
//