ID   A0A3B4F189_9CICH        Unreviewed;       307 AA.
AC   A0A3B4F189;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=USP domain-containing protein {ECO:0000259|PROSITE:PS50235};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000003738.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000003738.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B4F189; -.
DR   Ensembl; ENSPNYT00000003834.1; ENSPNYP00000003738.1; ENSPNYG00000002924.1.
DR   GeneTree; ENSGT00940000172369; -.
DR   Proteomes; UP000261460; Unplaced.
DR   GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR   CDD; cd02257; Peptidase_C19; 1.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR018200; USP_CS.
DR   InterPro; IPR028889; USP_dom.
DR   PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   PANTHER; PTHR24006:SF899; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   Pfam; PF00443; UCH; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS00972; USP_1; 1.
DR   PROSITE; PS00973; USP_2; 1.
DR   PROSITE; PS50235; USP_3; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..307
FT                   /note="USP domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017280700"
FT   DOMAIN          49..307
FT                   /note="USP"
FT                   /evidence="ECO:0000259|PROSITE:PS50235"
SQ   SEQUENCE   307 AA;  34534 MW;  55E4B0F01800131D CRC64;
     MILTVLISFP VHAADTQHIS EAPTGGASAN EQQEQVVKTT GRDEANKYHG LVNQGGTCYL
     NSVLQVLFMT KDFREAVTRN PGASQYIDHR LNTLFDKLKE NTAYTHEISS KLDINPVSIR
     GGAAECFEKI LSLTSPEASQ IFQGVLTHRN KCSTCSTETG TDDPFWTLPL QLVQSDTRDY
     SVTDAVAKYF SQSDAGGGNQ LYCDRCACKS DAAIKLEMRH HPDVLTLLLK KNKFDHQYQV
     CMKIRQEVIV PKTLQIPENQ TYELYAFVEH FGDLRSGHYT VTIKSQDDDR WYNFNDTCVT
     LVSLIDF
//