ID   A0A3B4FE07_9CICH        Unreviewed;       381 AA.
AC   A0A3B4FE07;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Otolin 1 {ECO:0000313|Ensembl:ENSPNYP00000008840.1};
OS   Pundamilia nyererei.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Haplochromini; Pundamilia.
OX   NCBI_TaxID=303518 {ECO:0000313|Ensembl:ENSPNYP00000008840.1, ECO:0000313|Proteomes:UP000261460};
RN   [1] {ECO:0000313|Ensembl:ENSPNYP00000008840.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR   AlphaFoldDB; A0A3B4FE07; -.
DR   Ensembl; ENSPNYT00000009049.1; ENSPNYP00000008840.1; ENSPNYG00000006696.1.
DR   GeneTree; ENSGT00940000155435; -.
DR   Proteomes; UP000261460; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.40; -; 1.
DR   InterPro; IPR001073; C1q_dom.
DR   InterPro; IPR008160; Collagen.
DR   InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
DR   PANTHER; PTHR15427:SF33; EMI DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR15427; EMILIN ELASTIN MICROFIBRIL INTERFACE-LOCATED PROTEIN ELASTIN MICROFIBRIL INTERFACER; 1.
DR   Pfam; PF00386; C1q; 1.
DR   Pfam; PF01391; Collagen; 3.
DR   PRINTS; PR00007; COMPLEMNTC1Q.
DR   SMART; SM00110; C1Q; 1.
DR   SUPFAM; SSF49842; TNF-like; 1.
DR   PROSITE; PS50871; C1Q; 1.
PE   4: Predicted;
KW   Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          245..381
FT                   /note="C1q"
FT                   /evidence="ECO:0000259|PROSITE:PS50871"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          114..197
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..20
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        159..179
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   381 AA;  40273 MW;  79EFC0B6250154EE CRC64;
     SCAKKVSPMR TTNPSHVFPQ HYPDSTGPPG VGPENYTLDY NECYFNFCEC CPPERGPRGL
     KGERGLTGID SLICFNVINY WATGEKGLTG AAGLPGPPGI SGDVGYKGEK GEVGLQGLKG
     EKGQKGEPGK NGTAGEKGEP GKEGPAGPPG VATVQGPKGD KGDRGECASY GEKGHKGEPG
     EPGAPGIPGA MGIPGQNGEP GVRGLEGPQG IRGIPGPRGE RGYPGMRGER GFRGFKGAKG
     SGSGVPQKHS AFSVGISPRK SFPPSGFPIR FDKVFYNEEN HFNITSNSFT CVYPGVYVFS
     FHITVRNQPL RATLVVNGSR RVRTRDSLYG QDIDQASTLV VLRLAAGDQV WMETLRDWNG
     AYASSEDDSI FSGFLLYSDK P
//